Near infrared luminescent-magnetic nanoparticles for bimodal imaging in vivo

I. V. Zelepukin, M. P. Nikitin, A. V. Nechaev, A. V. Zvyagin, P. I. Nikitin, S. M. Deyev

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The methods of multimodal imaging are very attractive for a variety of applications in the field of life sciences. Here, we report synthesis of luminescent magnetic nanostructures based on upconversion nanophosphors and superparamagnetic iron oxide nanoparticles for their bimodal detection in vivo. Poly(lactic-co-glycolic acid) copolymer matrix was used for stabilization of nanoparticles in physiological pH and influence of reaction conditions on final size of nanoagents was investigated. The particles were studied by dynamic light scattering and transmission electron microscopy methods. The obtained particles are attractive for biomodal imaging inside small animals in vivo by the methods of optical tomography and magnetic particle quantification methods.

Original languageEnglish
Title of host publicationProceedings - 2016 International Conference Laser Optics, LO 2016
PublisherInstitute of Electrical and Electronics Engineers Inc.
PagesS244
ISBN (Electronic)9781467397353
DOIs
Publication statusPublished - 23 Aug 2016
Externally publishedYes
Event2016 International Conference Laser Optics, LO 2016 - St. Petersburg, Russian Federation
Duration: 27 Jun 20161 Jul 2016

Conference

Conference2016 International Conference Laser Optics, LO 2016
CountryRussian Federation
CitySt. Petersburg
Period27.6.161.7.16

Keywords

  • bioimaging
  • luminescent tomography
  • magnetic detection
  • nanoparticles synthesis
  • spatial mapping

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics

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  • Cite this

    Zelepukin, I. V., Nikitin, M. P., Nechaev, A. V., Zvyagin, A. V., Nikitin, P. I., & Deyev, S. M. (2016). Near infrared luminescent-magnetic nanoparticles for bimodal imaging in vivo. In Proceedings - 2016 International Conference Laser Optics, LO 2016 (pp. S244). [7550011] Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/LO.2016.7550011