Near infrared luminescent-magnetic nanoparticles for bimodal imaging in vivo

Abstract

The methods of multimodal imaging are very attractive for a variety of applications in the field of life sciences. Here, we report synthesis of luminescent magnetic nanostructures based on upconversion nanophosphors and superparamagnetic iron oxide nanoparticles for their bimodal detection in vivo. Poly(lactic-co-glycolic acid) copolymer matrix was used for stabilization of nanoparticles in physiological pH and influence of reaction conditions on final size of nanoagents was investigated. The particles were studied by dynamic light scattering and transmission electron microscopy methods. The obtained particles are attractive for biomodal imaging inside small animals in vivo by the methods of optical tomography and magnetic particle quantification methods.

Original language	English
Title of host publication	Proceedings - 2016 International Conference Laser Optics, LO 2016
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	S244
ISBN (Electronic)	9781467397353
DOIs	https://doi.org/10.1109/LO.2016.7550011
Publication status	Published - 23 Aug 2016
Externally published	Yes
Event	2016 International Conference Laser Optics, LO 2016 - St. Petersburg, Russian Federation Duration: 27 Jun 2016 → 1 Jul 2016

Conference

Conference	2016 International Conference Laser Optics, LO 2016
Country	Russian Federation
City	St. Petersburg
Period	27.6.16 → 1.7.16

Keywords

bioimaging
luminescent tomography
magnetic detection
nanoparticles synthesis
spatial mapping

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Atomic and Molecular Physics, and Optics

Access to Document

10.1109/LO.2016.7550011

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Cite this

Near infrared luminescent-magnetic nanoparticles for bimodal imaging in vivo. / Zelepukin, I. V.; Nikitin, M. P.; Nechaev, A. V.; Zvyagin, A. V.; Nikitin, P. I.; Deyev, S. M.

Proceedings - 2016 International Conference Laser Optics, LO 2016. Institute of Electrical and Electronics Engineers Inc., 2016. p. S244 7550011.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Zelepukin, IV, Nikitin, MP, Nechaev, AV, Zvyagin, AV, Nikitin, PI & Deyev, SM 2016, Near infrared luminescent-magnetic nanoparticles for bimodal imaging in vivo. in Proceedings - 2016 International Conference Laser Optics, LO 2016., 7550011, Institute of Electrical and Electronics Engineers Inc., pp. S244, 2016 International Conference Laser Optics, LO 2016, St. Petersburg, Russian Federation, 27.6.16. https://doi.org/10.1109/LO.2016.7550011

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