Abstract
The methods of multimodal imaging are very attractive for a variety of applications in the field of life sciences. Here, we report synthesis of luminescent magnetic nanostructures based on upconversion nanophosphors and superparamagnetic iron oxide nanoparticles for their bimodal detection in vivo. Poly(lactic-co-glycolic acid) copolymer matrix was used for stabilization of nanoparticles in physiological pH and influence of reaction conditions on final size of nanoagents was investigated. The particles were studied by dynamic light scattering and transmission electron microscopy methods. The obtained particles are attractive for biomodal imaging inside small animals in vivo by the methods of optical tomography and magnetic particle quantification methods.
| Original language | English |
|---|---|
| Title of host publication | Proceedings - 2016 International Conference Laser Optics, LO 2016 |
| Publisher | Institute of Electrical and Electronics Engineers Inc. |
| Pages | S244 |
| ISBN (Electronic) | 9781467397353 |
| DOIs | |
| Publication status | Published - 23 Aug 2016 |
| Externally published | Yes |
| Event | 2016 International Conference Laser Optics, LO 2016 - St. Petersburg, Russian Federation Duration: 27 Jun 2016 → 1 Jul 2016 |
Conference
| Conference | 2016 International Conference Laser Optics, LO 2016 |
|---|---|
| Country | Russian Federation |
| City | St. Petersburg |
| Period | 27.6.16 → 1.7.16 |
Fingerprint
Keywords
- bioimaging
- luminescent tomography
- magnetic detection
- nanoparticles synthesis
- spatial mapping
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Atomic and Molecular Physics, and Optics
Cite this
Near infrared luminescent-magnetic nanoparticles for bimodal imaging in vivo. / Zelepukin, I. V.; Nikitin, M. P.; Nechaev, A. V.; Zvyagin, A. V.; Nikitin, P. I.; Deyev, S. M.
Proceedings - 2016 International Conference Laser Optics, LO 2016. Institute of Electrical and Electronics Engineers Inc., 2016. p. S244 7550011.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - Near infrared luminescent-magnetic nanoparticles for bimodal imaging in vivo
AU - Zelepukin, I. V.
AU - Nikitin, M. P.
AU - Nechaev, A. V.
AU - Zvyagin, A. V.
AU - Nikitin, P. I.
AU - Deyev, S. M.
PY - 2016/8/23
Y1 - 2016/8/23
N2 - The methods of multimodal imaging are very attractive for a variety of applications in the field of life sciences. Here, we report synthesis of luminescent magnetic nanostructures based on upconversion nanophosphors and superparamagnetic iron oxide nanoparticles for their bimodal detection in vivo. Poly(lactic-co-glycolic acid) copolymer matrix was used for stabilization of nanoparticles in physiological pH and influence of reaction conditions on final size of nanoagents was investigated. The particles were studied by dynamic light scattering and transmission electron microscopy methods. The obtained particles are attractive for biomodal imaging inside small animals in vivo by the methods of optical tomography and magnetic particle quantification methods.
AB - The methods of multimodal imaging are very attractive for a variety of applications in the field of life sciences. Here, we report synthesis of luminescent magnetic nanostructures based on upconversion nanophosphors and superparamagnetic iron oxide nanoparticles for their bimodal detection in vivo. Poly(lactic-co-glycolic acid) copolymer matrix was used for stabilization of nanoparticles in physiological pH and influence of reaction conditions on final size of nanoagents was investigated. The particles were studied by dynamic light scattering and transmission electron microscopy methods. The obtained particles are attractive for biomodal imaging inside small animals in vivo by the methods of optical tomography and magnetic particle quantification methods.
KW - bioimaging
KW - luminescent tomography
KW - magnetic detection
KW - nanoparticles synthesis
KW - spatial mapping
UR - http://www.scopus.com/inward/record.url?scp=84987927039&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84987927039&partnerID=8YFLogxK
U2 - 10.1109/LO.2016.7550011
DO - 10.1109/LO.2016.7550011
M3 - Conference contribution
SP - S244
BT - Proceedings - 2016 International Conference Laser Optics, LO 2016
PB - Institute of Electrical and Electronics Engineers Inc.
ER -