Abstract
Currently, nanotechnologies are widely used in science and industry. It is known that the application of drug delivery nanostructured carriers for biomedicine is one of the promising areas of nanotechnology. Nanostructured carriers can be used in the diagnosis process for detecting a neoplastic tumor cells in peripheral blood, for contrast enhancement on magnetic resonance imaging (MRI), as well as for targeted drug delivery to tumor tissues. Agents for the targeted delivery (nanoparticles, liposomes, microcapsules, and etc) can affect the healthy tissues and organs, cause side effects and have a toxic effect. Therefore, it necessary to study the morphological changes that occur not only in the "target", such as a tumor, but also the internal organs, taking place under the influence of both the agents for targeted drug delivery and physical impact induced remote controlled drug release. Thus, the aim of our work is selection of the most promising agents for targeted drug delivery to tumor and contrast agents for in vivo visualization of tumor tissue boundaries, as well as their impact on the organs and tissues as results of nanostructured object biodistribution.
| Original language | English |
|---|---|
| Title of host publication | Saratov Fall Meeting 2015 - Third International Symposium on Optics and Biophotonics; and Seventh Finnish-Russian Photonics and Laser Symposium (PALS) |
| Publisher | SPIE |
| Volume | 9917 |
| ISBN (Electronic) | 9781510602267 |
| DOIs | |
| Publication status | Published - 2016 |
| Externally published | Yes |
| Event | 3rd International Symposium on Optics and Biophotonics, SFM 2015 and 7th Finnish-Russian Photonics and Laser Symposium, PALS 2015 - Saratov, Russian Federation Duration: 22 Sep 2015 → 25 Sep 2015 |
Conference
| Conference | 3rd International Symposium on Optics and Biophotonics, SFM 2015 and 7th Finnish-Russian Photonics and Laser Symposium, PALS 2015 |
|---|---|
| Country | Russian Federation |
| City | Saratov |
| Period | 22.9.15 → 25.9.15 |
Fingerprint
Keywords
- Microcapsules
- MRI contast agents
- Nanoparticles
- Targeted drug delivery
ASJC Scopus subject areas
- Atomic and Molecular Physics, and Optics
- Electronic, Optical and Magnetic Materials
- Biomaterials
- Radiology Nuclear Medicine and imaging
Cite this
Nanoparticles and nanostructured carriers for drug delivery and contrast enhancement. / Godage, Olga S.; Bucharskaya, Alla B.; Navolokin, Nikita A.; German, Sergey V.; Zuev, Viktor V.; Terentuyk, Georgy S.; Maslyakova, Galina N.; Gorin, Dmitry A.
Saratov Fall Meeting 2015 - Third International Symposium on Optics and Biophotonics; and Seventh Finnish-Russian Photonics and Laser Symposium (PALS). Vol. 9917 SPIE, 2016. 99171H.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - Nanoparticles and nanostructured carriers for drug delivery and contrast enhancement
AU - Godage, Olga S.
AU - Bucharskaya, Alla B.
AU - Navolokin, Nikita A.
AU - German, Sergey V.
AU - Zuev, Viktor V.
AU - Terentuyk, Georgy S.
AU - Maslyakova, Galina N.
AU - Gorin, Dmitry A.
PY - 2016
Y1 - 2016
N2 - Currently, nanotechnologies are widely used in science and industry. It is known that the application of drug delivery nanostructured carriers for biomedicine is one of the promising areas of nanotechnology. Nanostructured carriers can be used in the diagnosis process for detecting a neoplastic tumor cells in peripheral blood, for contrast enhancement on magnetic resonance imaging (MRI), as well as for targeted drug delivery to tumor tissues. Agents for the targeted delivery (nanoparticles, liposomes, microcapsules, and etc) can affect the healthy tissues and organs, cause side effects and have a toxic effect. Therefore, it necessary to study the morphological changes that occur not only in the "target", such as a tumor, but also the internal organs, taking place under the influence of both the agents for targeted drug delivery and physical impact induced remote controlled drug release. Thus, the aim of our work is selection of the most promising agents for targeted drug delivery to tumor and contrast agents for in vivo visualization of tumor tissue boundaries, as well as their impact on the organs and tissues as results of nanostructured object biodistribution.
AB - Currently, nanotechnologies are widely used in science and industry. It is known that the application of drug delivery nanostructured carriers for biomedicine is one of the promising areas of nanotechnology. Nanostructured carriers can be used in the diagnosis process for detecting a neoplastic tumor cells in peripheral blood, for contrast enhancement on magnetic resonance imaging (MRI), as well as for targeted drug delivery to tumor tissues. Agents for the targeted delivery (nanoparticles, liposomes, microcapsules, and etc) can affect the healthy tissues and organs, cause side effects and have a toxic effect. Therefore, it necessary to study the morphological changes that occur not only in the "target", such as a tumor, but also the internal organs, taking place under the influence of both the agents for targeted drug delivery and physical impact induced remote controlled drug release. Thus, the aim of our work is selection of the most promising agents for targeted drug delivery to tumor and contrast agents for in vivo visualization of tumor tissue boundaries, as well as their impact on the organs and tissues as results of nanostructured object biodistribution.
KW - Microcapsules
KW - MRI contast agents
KW - Nanoparticles
KW - Targeted drug delivery
UR - http://www.scopus.com/inward/record.url?scp=84975074571&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84975074571&partnerID=8YFLogxK
U2 - 10.1117/12.2229872
DO - 10.1117/12.2229872
M3 - Conference contribution
VL - 9917
BT - Saratov Fall Meeting 2015 - Third International Symposium on Optics and Biophotonics; and Seventh Finnish-Russian Photonics and Laser Symposium (PALS)
PB - SPIE
ER -