Nanoparticles and nanostructured carriers for drug delivery and contrast enhancement

Olga S. Godage, Alla B. Bucharskaya, Nikita A. Navolokin, Sergey V. German, Viktor V. Zuev, Georgy S. Terentuyk, Galina N. Maslyakova, Dmitry A. Gorin

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Currently, nanotechnologies are widely used in science and industry. It is known that the application of drug delivery nanostructured carriers for biomedicine is one of the promising areas of nanotechnology. Nanostructured carriers can be used in the diagnosis process for detecting a neoplastic tumor cells in peripheral blood, for contrast enhancement on magnetic resonance imaging (MRI), as well as for targeted drug delivery to tumor tissues. Agents for the targeted delivery (nanoparticles, liposomes, microcapsules, and etc) can affect the healthy tissues and organs, cause side effects and have a toxic effect. Therefore, it necessary to study the morphological changes that occur not only in the "target", such as a tumor, but also the internal organs, taking place under the influence of both the agents for targeted drug delivery and physical impact induced remote controlled drug release. Thus, the aim of our work is selection of the most promising agents for targeted drug delivery to tumor and contrast agents for in vivo visualization of tumor tissue boundaries, as well as their impact on the organs and tissues as results of nanostructured object biodistribution.

Original languageEnglish
Title of host publicationSaratov Fall Meeting 2015 - Third International Symposium on Optics and Biophotonics; and Seventh Finnish-Russian Photonics and Laser Symposium (PALS)
PublisherSPIE
Volume9917
ISBN (Electronic)9781510602267
DOIs
Publication statusPublished - 2016
Externally publishedYes
Event3rd International Symposium on Optics and Biophotonics, SFM 2015 and 7th Finnish-Russian Photonics and Laser Symposium, PALS 2015 - Saratov, Russian Federation
Duration: 22 Sep 201525 Sep 2015

Conference

Conference3rd International Symposium on Optics and Biophotonics, SFM 2015 and 7th Finnish-Russian Photonics and Laser Symposium, PALS 2015
CountryRussian Federation
CitySaratov
Period22.9.1525.9.15

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Keywords

  • Microcapsules
  • MRI contast agents
  • Nanoparticles
  • Targeted drug delivery

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

Cite this

Godage, O. S., Bucharskaya, A. B., Navolokin, N. A., German, S. V., Zuev, V. V., Terentuyk, G. S., ... Gorin, D. A. (2016). Nanoparticles and nanostructured carriers for drug delivery and contrast enhancement. In Saratov Fall Meeting 2015 - Third International Symposium on Optics and Biophotonics; and Seventh Finnish-Russian Photonics and Laser Symposium (PALS) (Vol. 9917). [99171H] SPIE. https://doi.org/10.1117/12.2229872