Nanoparticles and nanostructured carriers for drug delivery and contrast enhancement

Abstract

Currently, nanotechnologies are widely used in science and industry. It is known that the application of drug delivery nanostructured carriers for biomedicine is one of the promising areas of nanotechnology. Nanostructured carriers can be used in the diagnosis process for detecting a neoplastic tumor cells in peripheral blood, for contrast enhancement on magnetic resonance imaging (MRI), as well as for targeted drug delivery to tumor tissues. Agents for the targeted delivery (nanoparticles, liposomes, microcapsules, and etc) can affect the healthy tissues and organs, cause side effects and have a toxic effect. Therefore, it necessary to study the morphological changes that occur not only in the "target", such as a tumor, but also the internal organs, taking place under the influence of both the agents for targeted drug delivery and physical impact induced remote controlled drug release. Thus, the aim of our work is selection of the most promising agents for targeted drug delivery to tumor and contrast agents for in vivo visualization of tumor tissue boundaries, as well as their impact on the organs and tissues as results of nanostructured object biodistribution.

Original language	English
Title of host publication	Saratov Fall Meeting 2015 - Third International Symposium on Optics and Biophotonics; and Seventh Finnish-Russian Photonics and Laser Symposium (PALS)
Publisher	SPIE
Volume	9917
ISBN (Electronic)	9781510602267
DOIs	https://doi.org/10.1117/12.2229872
Publication status	Published - 2016
Externally published	Yes
Event	3rd International Symposium on Optics and Biophotonics, SFM 2015 and 7th Finnish-Russian Photonics and Laser Symposium, PALS 2015 - Saratov, Russian Federation Duration: 22 Sep 2015 → 25 Sep 2015

Conference

Conference	3rd International Symposium on Optics and Biophotonics, SFM 2015 and 7th Finnish-Russian Photonics and Laser Symposium, PALS 2015
Country	Russian Federation
City	Saratov
Period	22.9.15 → 25.9.15

Keywords

Microcapsules
MRI contast agents
Nanoparticles
Targeted drug delivery

ASJC Scopus subject areas

Atomic and Molecular Physics, and Optics
Electronic, Optical and Magnetic Materials
Biomaterials
Radiology Nuclear Medicine and imaging

Access to Document

10.1117/12.2229872

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Cite this

Godage, O. S., Bucharskaya, A. B., Navolokin, N. A., German, S. V., Zuev, V. V., Terentuyk, G. S., Maslyakova, G. N., & Gorin, D. A. (2016). Nanoparticles and nanostructured carriers for drug delivery and contrast enhancement. In Saratov Fall Meeting 2015 - Third International Symposium on Optics and Biophotonics; and Seventh Finnish-Russian Photonics and Laser Symposium (PALS) (Vol. 9917). [99171H] SPIE. https://doi.org/10.1117/12.2229872

Nanoparticles and nanostructured carriers for drug delivery and contrast enhancement. / Godage, Olga S.; Bucharskaya, Alla B.; Navolokin, Nikita A.; German, Sergey V.; Zuev, Viktor V.; Terentuyk, Georgy S.; Maslyakova, Galina N.; Gorin, Dmitry A.

Saratov Fall Meeting 2015 - Third International Symposium on Optics and Biophotonics; and Seventh Finnish-Russian Photonics and Laser Symposium (PALS). Vol. 9917 SPIE, 2016. 99171H.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Godage, OS, Bucharskaya, AB, Navolokin, NA, German, SV, Zuev, VV, Terentuyk, GS, Maslyakova, GN & Gorin, DA 2016, Nanoparticles and nanostructured carriers for drug delivery and contrast enhancement. in Saratov Fall Meeting 2015 - Third International Symposium on Optics and Biophotonics; and Seventh Finnish-Russian Photonics and Laser Symposium (PALS). vol. 9917, 99171H, SPIE, 3rd International Symposium on Optics and Biophotonics, SFM 2015 and 7th Finnish-Russian Photonics and Laser Symposium, PALS 2015, Saratov, Russian Federation, 22.9.15. https://doi.org/10.1117/12.2229872

Godage OS, Bucharskaya AB, Navolokin NA, German SV, Zuev VV, Terentuyk GS et al. Nanoparticles and nanostructured carriers for drug delivery and contrast enhancement. In Saratov Fall Meeting 2015 - Third International Symposium on Optics and Biophotonics; and Seventh Finnish-Russian Photonics and Laser Symposium (PALS). Vol. 9917. SPIE. 2016. 99171H https://doi.org/10.1117/12.2229872

Godage, Olga S. ; Bucharskaya, Alla B. ; Navolokin, Nikita A. ; German, Sergey V. ; Zuev, Viktor V. ; Terentuyk, Georgy S. ; Maslyakova, Galina N. ; Gorin, Dmitry A. / Nanoparticles and nanostructured carriers for drug delivery and contrast enhancement. Saratov Fall Meeting 2015 - Third International Symposium on Optics and Biophotonics; and Seventh Finnish-Russian Photonics and Laser Symposium (PALS). Vol. 9917 SPIE, 2016.

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AU - Zuev, Viktor V.

AU - Terentuyk, Georgy S.

AU - Maslyakova, Galina N.

AU - Gorin, Dmitry A.

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AB - Currently, nanotechnologies are widely used in science and industry. It is known that the application of drug delivery nanostructured carriers for biomedicine is one of the promising areas of nanotechnology. Nanostructured carriers can be used in the diagnosis process for detecting a neoplastic tumor cells in peripheral blood, for contrast enhancement on magnetic resonance imaging (MRI), as well as for targeted drug delivery to tumor tissues. Agents for the targeted delivery (nanoparticles, liposomes, microcapsules, and etc) can affect the healthy tissues and organs, cause side effects and have a toxic effect. Therefore, it necessary to study the morphological changes that occur not only in the "target", such as a tumor, but also the internal organs, taking place under the influence of both the agents for targeted drug delivery and physical impact induced remote controlled drug release. Thus, the aim of our work is selection of the most promising agents for targeted drug delivery to tumor and contrast agents for in vivo visualization of tumor tissue boundaries, as well as their impact on the organs and tissues as results of nanostructured object biodistribution.

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