Nanoengineered colloidal probes for raman-based detection of biomolecules inside living cells

Alexey Yashchenok, Admir Masic, Dmitry Gorin, Bong Sup Shim, Nicholas A. Kotov, Peter Fratzl, Helmuth Möhwald, Andre Skirtach

Research output: Contribution to journalArticle

42 Citations (Scopus)

Abstract

Gold nanoparticle aggregate carbon nanotube functionalized colloidal particles serve as an efficient platform for probing the intracellular environment. The probes provide the means of effective localization of signal and detection of molecular fingerprints of biomolecules in living cells. The approach demonstrated in this work opens significant opportunities in molecular imaging as well as intracellular sensing and trafficking.

Original languageEnglish
Pages (from-to)351-356
Number of pages6
JournalSmall
Volume9
Issue number3
DOIs
Publication statusPublished - 11 Feb 2013
Externally publishedYes

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Keywords

  • carbon nanotubes
  • chemical imaging
  • gold nanoparticles
  • Raman spectroscopy
  • SERS

ASJC Scopus subject areas

  • Biomaterials
  • Engineering (miscellaneous)
  • Biotechnology
  • Medicine(all)

Cite this

Yashchenok, A., Masic, A., Gorin, D., Shim, B. S., Kotov, N. A., Fratzl, P., Möhwald, H., & Skirtach, A. (2013). Nanoengineered colloidal probes for raman-based detection of biomolecules inside living cells. Small, 9(3), 351-356. https://doi.org/10.1002/smll.201201494