Nanoencapsulated and microencapsulated SERS platforms for biomedical analysis

Abstract

The problems of layer-by-layer-based surface enhancement Raman scattering (SERS)-sensor application for pharmaceutical analysis were discussed. Layer-by-layer (LbL) method allows fabrication of encapsulated SERS platforms with high reproducibility of enhancement factor and increased signal/noise ratio of Raman scattering. LbL encapsulation approach opens an avenue to implement a novel type of theranostic systems combining SERS based sensing and drug delivery in one entity. The area of encapsulation development toward smart multifunctional theranostic systems could bring benefits for personalized medicine and should minimize costs and resources at preclinical and clinical study in pharmacology while testing new bioactive compounds.

Original language	English
Pages (from-to)	149-158
Number of pages	10
Journal	Current Opinion in Pharmacology
Volume	18
DOIs	https://doi.org/10.1016/j.coph.2014.10.002
Publication status	Published - 2014
Externally published	Yes

ASJC Scopus subject areas

Drug Discovery
Pharmacology
Medicine(all)

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10.1016/j.coph.2014.10.002

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Stetciura, I. Y., Markin, A. V., Bratashov, D. N., Sukhorukov, G. B., & Gorin, D. A. (2014). Nanoencapsulated and microencapsulated SERS platforms for biomedical analysis. Current Opinion in Pharmacology, 18, 149-158. https://doi.org/10.1016/j.coph.2014.10.002

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abstract = "The problems of layer-by-layer-based surface enhancement Raman scattering (SERS)-sensor application for pharmaceutical analysis were discussed. Layer-by-layer (LbL) method allows fabrication of encapsulated SERS platforms with high reproducibility of enhancement factor and increased signal/noise ratio of Raman scattering. LbL encapsulation approach opens an avenue to implement a novel type of theranostic systems combining SERS based sensing and drug delivery in one entity. The area of encapsulation development toward smart multifunctional theranostic systems could bring benefits for personalized medicine and should minimize costs and resources at preclinical and clinical study in pharmacology while testing new bioactive compounds.",

author = "Stetciura, {Inna Y.} and Markin, {Alexey V.} and Bratashov, {Daniil N.} and Sukhorukov, {Gleb B.} and Gorin, {Dmitry A.}",

year = "2014",

doi = "10.1016/j.coph.2014.10.002",

language = "English",

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journal = "Current Opinion in Pharmacology",

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AU - Stetciura, Inna Y.

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AU - Bratashov, Daniil N.

AU - Sukhorukov, Gleb B.

AU - Gorin, Dmitry A.

PY - 2014

Y1 - 2014

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AB - The problems of layer-by-layer-based surface enhancement Raman scattering (SERS)-sensor application for pharmaceutical analysis were discussed. Layer-by-layer (LbL) method allows fabrication of encapsulated SERS platforms with high reproducibility of enhancement factor and increased signal/noise ratio of Raman scattering. LbL encapsulation approach opens an avenue to implement a novel type of theranostic systems combining SERS based sensing and drug delivery in one entity. The area of encapsulation development toward smart multifunctional theranostic systems could bring benefits for personalized medicine and should minimize costs and resources at preclinical and clinical study in pharmacology while testing new bioactive compounds.

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