Abstract
Purpose: To determine abilities and principal features of prospective scintigraphic evaluation of endovascular treatment results of coronary artery disease (CAD) using thallium-199 perfusion single-photon emission computed tomography. Material and methods: Forty CAD patients were investigated by perfusion scintigraphy before and 2-3 weeks, 3-6 months and 1-2 years after coronary artery stenting. The character and size of perfusion defects and presence of the reverse radionuclide redistribution phenomenon were estimated. Results: The coronary stenting almost results to the 80 % decrease of mean size of transitory ischemic zones. The presence of reversible perfusion defects after operation was bound up with the incomplete revascularization or with X-syndrome. At later time periods of the observation, the unfavorable course of coronary insufficiency was due to coronary artery restenosis. Mean value of persistent perfusion defects has not changed after endovascular treatment, but 11 patients have demonstrated disappearance or volume decrease of stable ischemic zones at early and late postoperative period, that has testified to myocardial viability. In group of patients with rapid wash-out of thallium ("reverse redistribution" (RR)) there was the occurrence of new reversible and stable perfusion defects in projection of previous existence of RR. The condition of microcirculation of the heart muscle has not undergo remarkable changes in the group of patients without RR. Conclusion: Myocardium thallium-199 chloride perfusion scintigraphy is the objective method for evaluation of coronary stenting results and restenosis diagnostics. It allows to determine hibernating myocardium in CAD patients and discover unfavorable scintigraphy predictors for possible cardiovascular events.
| Original language | English |
|---|---|
| Pages (from-to) | 45-53 |
| Number of pages | 9 |
| Journal | Meditsinskaya Radiologiya I Radiatsionnaya Bezopasnost' |
| Volume | 49 |
| Issue number | 4 |
| Publication status | Published - 2004 |
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Keywords
- Balloon angioplasty
- Myocardium perfusion scintigraphy
- Reverse redistribution of thallium
- Stenting of coronary arteries
ASJC Scopus subject areas
- Nuclear Energy and Engineering
Cite this
Myocardium perfusion scintigraphy in evaluation of endovascular treatment results of coronary artery disease. / Lishmanov, Yu B.; Vesoina, J. V.; Rybalchenko, E. V.; Krylov, A. L.
In: Meditsinskaya Radiologiya I Radiatsionnaya Bezopasnost', Vol. 49, No. 4, 2004, p. 45-53.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Myocardium perfusion scintigraphy in evaluation of endovascular treatment results of coronary artery disease
AU - Lishmanov, Yu B.
AU - Vesoina, J. V.
AU - Rybalchenko, E. V.
AU - Krylov, A. L.
PY - 2004
Y1 - 2004
N2 - Purpose: To determine abilities and principal features of prospective scintigraphic evaluation of endovascular treatment results of coronary artery disease (CAD) using thallium-199 perfusion single-photon emission computed tomography. Material and methods: Forty CAD patients were investigated by perfusion scintigraphy before and 2-3 weeks, 3-6 months and 1-2 years after coronary artery stenting. The character and size of perfusion defects and presence of the reverse radionuclide redistribution phenomenon were estimated. Results: The coronary stenting almost results to the 80 % decrease of mean size of transitory ischemic zones. The presence of reversible perfusion defects after operation was bound up with the incomplete revascularization or with X-syndrome. At later time periods of the observation, the unfavorable course of coronary insufficiency was due to coronary artery restenosis. Mean value of persistent perfusion defects has not changed after endovascular treatment, but 11 patients have demonstrated disappearance or volume decrease of stable ischemic zones at early and late postoperative period, that has testified to myocardial viability. In group of patients with rapid wash-out of thallium ("reverse redistribution" (RR)) there was the occurrence of new reversible and stable perfusion defects in projection of previous existence of RR. The condition of microcirculation of the heart muscle has not undergo remarkable changes in the group of patients without RR. Conclusion: Myocardium thallium-199 chloride perfusion scintigraphy is the objective method for evaluation of coronary stenting results and restenosis diagnostics. It allows to determine hibernating myocardium in CAD patients and discover unfavorable scintigraphy predictors for possible cardiovascular events.
AB - Purpose: To determine abilities and principal features of prospective scintigraphic evaluation of endovascular treatment results of coronary artery disease (CAD) using thallium-199 perfusion single-photon emission computed tomography. Material and methods: Forty CAD patients were investigated by perfusion scintigraphy before and 2-3 weeks, 3-6 months and 1-2 years after coronary artery stenting. The character and size of perfusion defects and presence of the reverse radionuclide redistribution phenomenon were estimated. Results: The coronary stenting almost results to the 80 % decrease of mean size of transitory ischemic zones. The presence of reversible perfusion defects after operation was bound up with the incomplete revascularization or with X-syndrome. At later time periods of the observation, the unfavorable course of coronary insufficiency was due to coronary artery restenosis. Mean value of persistent perfusion defects has not changed after endovascular treatment, but 11 patients have demonstrated disappearance or volume decrease of stable ischemic zones at early and late postoperative period, that has testified to myocardial viability. In group of patients with rapid wash-out of thallium ("reverse redistribution" (RR)) there was the occurrence of new reversible and stable perfusion defects in projection of previous existence of RR. The condition of microcirculation of the heart muscle has not undergo remarkable changes in the group of patients without RR. Conclusion: Myocardium thallium-199 chloride perfusion scintigraphy is the objective method for evaluation of coronary stenting results and restenosis diagnostics. It allows to determine hibernating myocardium in CAD patients and discover unfavorable scintigraphy predictors for possible cardiovascular events.
KW - Balloon angioplasty
KW - Myocardium perfusion scintigraphy
KW - Reverse redistribution of thallium
KW - Stenting of coronary arteries
UR - http://www.scopus.com/inward/record.url?scp=5644244364&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=5644244364&partnerID=8YFLogxK
M3 - Article
VL - 49
SP - 45
EP - 53
JO - Meditsinskaya Radiologiya I Radiatsionnaya Bezopasnost'
JF - Meditsinskaya Radiologiya I Radiatsionnaya Bezopasnost'
SN - 0025-8334
IS - 4
ER -