Abstract
Purpose of the work is to study the diagnostic value of myocardial scintigraphy with 199Tl and 99mTc-MIBI for detecting coronary ischemia. Thallium-199 myocardial imaging was carried out in 160 patients: 105 with and 55 without coronary disease. Planar scintigraphy and single-photon emission computer-aided tomography (SPECT) with 99mTc-MIBI were carried out in 35 coronary patients and 27 controls. High sensitivity (92%) and specificity (84%) of 199Tl myocardial imaging for the diagnosis of coronary disease are demonstrated. The specificity of 99mTc-MIBI was 85% and sensitivity 91%, for SPECT 89 and 94%, respectively. The incidence of perfusion defect detection by both radiopharmaceuticals increased with the number of involved coronary arteries and in the presence of postinfarction cardiosclerosis. A significantly lower dose loading on the patients allows to recommend 199Tl and 99mTc-MIBI for scintigraphic diagnosis of coronary heart disease.
| Original language | English |
|---|---|
| Pages (from-to) | 20-27 |
| Number of pages | 8 |
| Journal | Changjiang Liuyu Ziyuan Yu Huanjing/Resources and Environment in the Yangtze Valley |
| Volume | 7 |
| Issue number | 4 |
| Publication status | Published - 1998 |
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Myocardial perfusion scintigraphy in the diagnosis of coronary heart disease. / Lishmanov, Yu B.; Chernov, V. I.
In: Changjiang Liuyu Ziyuan Yu Huanjing/Resources and Environment in the Yangtze Valley, Vol. 7, No. 4, 1998, p. 20-27.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Myocardial perfusion scintigraphy in the diagnosis of coronary heart disease
AU - Lishmanov, Yu B.
AU - Chernov, V. I.
PY - 1998
Y1 - 1998
N2 - Purpose of the work is to study the diagnostic value of myocardial scintigraphy with 199Tl and 99mTc-MIBI for detecting coronary ischemia. Thallium-199 myocardial imaging was carried out in 160 patients: 105 with and 55 without coronary disease. Planar scintigraphy and single-photon emission computer-aided tomography (SPECT) with 99mTc-MIBI were carried out in 35 coronary patients and 27 controls. High sensitivity (92%) and specificity (84%) of 199Tl myocardial imaging for the diagnosis of coronary disease are demonstrated. The specificity of 99mTc-MIBI was 85% and sensitivity 91%, for SPECT 89 and 94%, respectively. The incidence of perfusion defect detection by both radiopharmaceuticals increased with the number of involved coronary arteries and in the presence of postinfarction cardiosclerosis. A significantly lower dose loading on the patients allows to recommend 199Tl and 99mTc-MIBI for scintigraphic diagnosis of coronary heart disease.
AB - Purpose of the work is to study the diagnostic value of myocardial scintigraphy with 199Tl and 99mTc-MIBI for detecting coronary ischemia. Thallium-199 myocardial imaging was carried out in 160 patients: 105 with and 55 without coronary disease. Planar scintigraphy and single-photon emission computer-aided tomography (SPECT) with 99mTc-MIBI were carried out in 35 coronary patients and 27 controls. High sensitivity (92%) and specificity (84%) of 199Tl myocardial imaging for the diagnosis of coronary disease are demonstrated. The specificity of 99mTc-MIBI was 85% and sensitivity 91%, for SPECT 89 and 94%, respectively. The incidence of perfusion defect detection by both radiopharmaceuticals increased with the number of involved coronary arteries and in the presence of postinfarction cardiosclerosis. A significantly lower dose loading on the patients allows to recommend 199Tl and 99mTc-MIBI for scintigraphic diagnosis of coronary heart disease.
UR - http://www.scopus.com/inward/record.url?scp=0031600022&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0031600022&partnerID=8YFLogxK
M3 - Article
VL - 7
SP - 20
EP - 27
JO - Changjiang Liuyu Ziyuan Yu Huanjing/Resources and Environment in the Yangtze Valley
JF - Changjiang Liuyu Ziyuan Yu Huanjing/Resources and Environment in the Yangtze Valley
SN - 1004-8227
IS - 4
ER -