Myocardial perfusion scintigraphy in the diagnosis of coronary heart disease

Abstract

Purpose of the work is to study the diagnostic value of myocardial scintigraphy with ¹⁹⁹Tl and ^99mTc-MIBI for detecting coronary ischemia. Thallium-199 myocardial imaging was carried out in 160 patients: 105 with and 55 without coronary disease. Planar scintigraphy and single-photon emission computer-aided tomography (SPECT) with ^99mTc-MIBI were carried out in 35 coronary patients and 27 controls. High sensitivity (92%) and specificity (84%) of ¹⁹⁹Tl myocardial imaging for the diagnosis of coronary disease are demonstrated. The specificity of ^99mTc-MIBI was 85% and sensitivity 91%, for SPECT 89 and 94%, respectively. The incidence of perfusion defect detection by both radiopharmaceuticals increased with the number of involved coronary arteries and in the presence of postinfarction cardiosclerosis. A significantly lower dose loading on the patients allows to recommend ¹⁹⁹Tl and ^99mTc-MIBI for scintigraphic diagnosis of coronary heart disease.

Original language	English
Pages (from-to)	20-27
Number of pages	8
Journal	Changjiang Liuyu Ziyuan Yu Huanjing/Resources and Environment in the Yangtze Valley
Volume	7
Issue number	4
Publication status	Published - 1998

ASJC Scopus subject areas

Engineering(all)

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title = "Myocardial perfusion scintigraphy in the diagnosis of coronary heart disease",

abstract = "Purpose of the work is to study the diagnostic value of myocardial scintigraphy with 199Tl and 99mTc-MIBI for detecting coronary ischemia. Thallium-199 myocardial imaging was carried out in 160 patients: 105 with and 55 without coronary disease. Planar scintigraphy and single-photon emission computer-aided tomography (SPECT) with 99mTc-MIBI were carried out in 35 coronary patients and 27 controls. High sensitivity (92%) and specificity (84%) of 199Tl myocardial imaging for the diagnosis of coronary disease are demonstrated. The specificity of 99mTc-MIBI was 85% and sensitivity 91%, for SPECT 89 and 94%, respectively. The incidence of perfusion defect detection by both radiopharmaceuticals increased with the number of involved coronary arteries and in the presence of postinfarction cardiosclerosis. A significantly lower dose loading on the patients allows to recommend 199Tl and 99mTc-MIBI for scintigraphic diagnosis of coronary heart disease.",

author = "Lishmanov, {Yu B.} and Chernov, {V. I.}",

year = "1998",

language = "English",

volume = "7",

pages = "20--27",

journal = "Changjiang Liuyu Ziyuan Yu Huanjing/Resources and Environment in the Yangtze Valley",

issn = "1004-8227",

publisher = "Kexue Chubaneshe/Science Press",

number = "4",

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T1 - Myocardial perfusion scintigraphy in the diagnosis of coronary heart disease

AU - Lishmanov, Yu B.

AU - Chernov, V. I.

PY - 1998

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N2 - Purpose of the work is to study the diagnostic value of myocardial scintigraphy with 199Tl and 99mTc-MIBI for detecting coronary ischemia. Thallium-199 myocardial imaging was carried out in 160 patients: 105 with and 55 without coronary disease. Planar scintigraphy and single-photon emission computer-aided tomography (SPECT) with 99mTc-MIBI were carried out in 35 coronary patients and 27 controls. High sensitivity (92%) and specificity (84%) of 199Tl myocardial imaging for the diagnosis of coronary disease are demonstrated. The specificity of 99mTc-MIBI was 85% and sensitivity 91%, for SPECT 89 and 94%, respectively. The incidence of perfusion defect detection by both radiopharmaceuticals increased with the number of involved coronary arteries and in the presence of postinfarction cardiosclerosis. A significantly lower dose loading on the patients allows to recommend 199Tl and 99mTc-MIBI for scintigraphic diagnosis of coronary heart disease.

AB - Purpose of the work is to study the diagnostic value of myocardial scintigraphy with 199Tl and 99mTc-MIBI for detecting coronary ischemia. Thallium-199 myocardial imaging was carried out in 160 patients: 105 with and 55 without coronary disease. Planar scintigraphy and single-photon emission computer-aided tomography (SPECT) with 99mTc-MIBI were carried out in 35 coronary patients and 27 controls. High sensitivity (92%) and specificity (84%) of 199Tl myocardial imaging for the diagnosis of coronary disease are demonstrated. The specificity of 99mTc-MIBI was 85% and sensitivity 91%, for SPECT 89 and 94%, respectively. The incidence of perfusion defect detection by both radiopharmaceuticals increased with the number of involved coronary arteries and in the presence of postinfarction cardiosclerosis. A significantly lower dose loading on the patients allows to recommend 199Tl and 99mTc-MIBI for scintigraphic diagnosis of coronary heart disease.

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