Abstract
The results of research on three types of carbon nanofibers influence on an organism of Wistar rats at oral introduction with food in a dose of 500 mg per kilogram of a body weight within 14 days are presented. According to the results of electronic microscopy, carbon nanofibers had the following linear sizes: an average diameter is 85 nm and a length is about 5-50 μm. The influence of nanofibers on a histologic structure of stomach, intestines, and liver of rats is shown. The response to mechanical irritation is noted in signs as follows: raised mucus production, mucosal thickening, lymphoid follicles enlargement, vacuolation and necrosis in some cases.
| Original language | English |
|---|---|
| Article number | BM-075-15 |
| Journal | Biology and Medicine |
| Volume | 7 |
| Issue number | 2 |
| Publication status | Published - 2015 |
| Externally published | Yes |
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Keywords
- Carbon nanofibers
- Toxicity
- Wistar rats
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
Cite this
Morphological assessment of influence of carbon nanofibers on digestive organs of wistar rats upon oral administration. / Golokhvast, Kirill Sergeevich; Sayapina, Nina Valentinovna; Batalova, Tatyana Anatolievna; Sergievich, Alexander Alexandrovich; Mishakov, Ilya Vladimirovich; Vedyagin, Alexey Anatolievich; Novikov, Mikhail Alexandrovich; Agoshkov, Alexander Ivanovich; Petukhov, Valery Ivanovich; Drozd, Vladimir Alexandrovich; Ugay, Sergey Maksimovich; Chaika, Vladimir Viktorovich.
In: Biology and Medicine, Vol. 7, No. 2, BM-075-15, 2015.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Morphological assessment of influence of carbon nanofibers on digestive organs of wistar rats upon oral administration
AU - Golokhvast, Kirill Sergeevich
AU - Sayapina, Nina Valentinovna
AU - Batalova, Tatyana Anatolievna
AU - Sergievich, Alexander Alexandrovich
AU - Mishakov, Ilya Vladimirovich
AU - Vedyagin, Alexey Anatolievich
AU - Novikov, Mikhail Alexandrovich
AU - Agoshkov, Alexander Ivanovich
AU - Petukhov, Valery Ivanovich
AU - Drozd, Vladimir Alexandrovich
AU - Ugay, Sergey Maksimovich
AU - Chaika, Vladimir Viktorovich
PY - 2015
Y1 - 2015
N2 - The results of research on three types of carbon nanofibers influence on an organism of Wistar rats at oral introduction with food in a dose of 500 mg per kilogram of a body weight within 14 days are presented. According to the results of electronic microscopy, carbon nanofibers had the following linear sizes: an average diameter is 85 nm and a length is about 5-50 μm. The influence of nanofibers on a histologic structure of stomach, intestines, and liver of rats is shown. The response to mechanical irritation is noted in signs as follows: raised mucus production, mucosal thickening, lymphoid follicles enlargement, vacuolation and necrosis in some cases.
AB - The results of research on three types of carbon nanofibers influence on an organism of Wistar rats at oral introduction with food in a dose of 500 mg per kilogram of a body weight within 14 days are presented. According to the results of electronic microscopy, carbon nanofibers had the following linear sizes: an average diameter is 85 nm and a length is about 5-50 μm. The influence of nanofibers on a histologic structure of stomach, intestines, and liver of rats is shown. The response to mechanical irritation is noted in signs as follows: raised mucus production, mucosal thickening, lymphoid follicles enlargement, vacuolation and necrosis in some cases.
KW - Carbon nanofibers
KW - Toxicity
KW - Wistar rats
UR - http://www.scopus.com/inward/record.url?scp=84928729407&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84928729407&partnerID=8YFLogxK
M3 - Article
VL - 7
JO - Biology and Medicine
JF - Biology and Medicine
SN - 0974-8369
IS - 2
M1 - BM-075-15
ER -