Modulating effect of μ-opiate receptor ligands on adrenergic stage in pathogenesis of stress-induced damage to the heart

Yu B. Lishmanov, N. V. Naryzhnaya, Yu G. Revinskaya, L. N. Maslov

Research output: Contribution to journalArticle

Abstract

The agonists of μ-opiate receptors, DAGO and DALDA, prevent stress-induced enhancement of 99mTc-pyrophosphate accumulation in the myocardium, which attests to cardioprotective activity of these opioids. This phenomenon is presumably related to modulating effect of these agents on the adrenergic stage in pathogenesis of stress-induced damage to the heart.

Original languageEnglish
Pages (from-to)1095-1097
Number of pages3
JournalBulletin of Experimental Biology and Medicine
Volume126
Issue number11
Publication statusPublished - Nov 1998

Fingerprint

Technetium Tc 99m Pyrophosphate
Ala(2)-MePhe(4)-Gly(5)-enkephalin
Opioid Receptors
Adrenergic Agents
Opioid Analgesics
Myocardium
Ligands
tyrosyl-arginyl-phenylalanyl-lysinamide

Keywords

  • Catecholamines
  • Opiate receptors
  • Stress

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Modulating effect of μ-opiate receptor ligands on adrenergic stage in pathogenesis of stress-induced damage to the heart. / Lishmanov, Yu B.; Naryzhnaya, N. V.; Revinskaya, Yu G.; Maslov, L. N.

In: Bulletin of Experimental Biology and Medicine, Vol. 126, No. 11, 11.1998, p. 1095-1097.

Research output: Contribution to journalArticle

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