TY - JOUR
T1 - Modification of titanium surface via Ag-, Sr- and Si-containing micro-arc calcium phosphate coating
AU - Sedelnikova, Mariya B.
AU - Komarova, Ekaterina G.
AU - Sharkeev, Yurii P.
AU - Ugodchikova, Anna V.
AU - Tolkacheva, Tatiana V.
AU - Rau, Julietta V.
AU - Buyko, Evgeny E.
AU - Ivanov, Vladimir V.
AU - Sheikin, Vladimir V.
PY - 2019/12/1
Y1 - 2019/12/1
N2 - The current research is devoted to the study of the modification of the titanium implants by the micro-arc oxidation with bioactive calcium phosphate coatings containing Ag or Sr and Si elements. The coatings’ microstructure, phase composition, morphology, physicochemical and biological properties were examined by scanning electron microscopy (SEM), transmission electron microscopy (TEM), energy-dispersive X-ray spectroscopy (EDX) and X-ray diffraction (XRD). Ag-containing and Sr-Si-incorporated coatings were formed in alkaline and acid electrolytes, respectively. The formation of the coatings occurred at different ranges of the applied voltages, which led to the significant difference in the coatings properties. The trace elements Ag, Sr and Si participated intensively in the plasma-chemical reactions of the micro-arc coatings formation. Ag-containing coatings demonstrated strong antibacterial effect against Staphylococcus aureus AТСС 6538-P. MTT in vitro test with 3T3-L1 fibroblasts showed no cytotoxicity appearance on Sr-Si-incorporated coatings.
AB - The current research is devoted to the study of the modification of the titanium implants by the micro-arc oxidation with bioactive calcium phosphate coatings containing Ag or Sr and Si elements. The coatings’ microstructure, phase composition, morphology, physicochemical and biological properties were examined by scanning electron microscopy (SEM), transmission electron microscopy (TEM), energy-dispersive X-ray spectroscopy (EDX) and X-ray diffraction (XRD). Ag-containing and Sr-Si-incorporated coatings were formed in alkaline and acid electrolytes, respectively. The formation of the coatings occurred at different ranges of the applied voltages, which led to the significant difference in the coatings properties. The trace elements Ag, Sr and Si participated intensively in the plasma-chemical reactions of the micro-arc coatings formation. Ag-containing coatings demonstrated strong antibacterial effect against Staphylococcus aureus AТСС 6538-P. MTT in vitro test with 3T3-L1 fibroblasts showed no cytotoxicity appearance on Sr-Si-incorporated coatings.
KW - Antibacterial activity
KW - Biocoatings
KW - Micro-arc oxidation
KW - Titanium substrate
KW - Trace elements
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UR - http://www.scopus.com/inward/citedby.url?scp=85073644885&partnerID=8YFLogxK
U2 - 10.1016/j.bioactmat.2019.07.001
DO - 10.1016/j.bioactmat.2019.07.001
M3 - Article
AN - SCOPUS:85073644885
VL - 4
SP - 224
EP - 235
JO - Bioactive Materials
JF - Bioactive Materials
SN - 2452-199X
ER -