Modification of titanium surface via Ag-, Sr- and Si-containing micro-arc calcium phosphate coating

Mariya B. Sedelnikova, Ekaterina G. Komarova, Yurii P. Sharkeev, Anna V. Ugodchikova, Tatiana V. Tolkacheva, Julietta V. Rau, Evgeny E. Buyko, Vladimir V. Ivanov, Vladimir V. Sheikin

Research output: Contribution to journalArticlepeer-review

26 Citations (Scopus)


The current research is devoted to the study of the modification of the titanium implants by the micro-arc oxidation with bioactive calcium phosphate coatings containing Ag or Sr and Si elements. The coatings’ microstructure, phase composition, morphology, physicochemical and biological properties were examined by scanning electron microscopy (SEM), transmission electron microscopy (TEM), energy-dispersive X-ray spectroscopy (EDX) and X-ray diffraction (XRD). Ag-containing and Sr-Si-incorporated coatings were formed in alkaline and acid electrolytes, respectively. The formation of the coatings occurred at different ranges of the applied voltages, which led to the significant difference in the coatings properties. The trace elements Ag, Sr and Si participated intensively in the plasma-chemical reactions of the micro-arc coatings formation. Ag-containing coatings demonstrated strong antibacterial effect against Staphylococcus aureus AТСС 6538-P. MTT in vitro test with 3T3-L1 fibroblasts showed no cytotoxicity appearance on Sr-Si-incorporated coatings.

Original languageEnglish
Pages (from-to)224-235
Number of pages12
JournalBioactive Materials
Publication statusPublished - 1 Dec 2019


  • Antibacterial activity
  • Biocoatings
  • Micro-arc oxidation
  • Titanium substrate
  • Trace elements

ASJC Scopus subject areas

  • Biotechnology
  • Biomaterials
  • Biomedical Engineering

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