Abstract
It was established that CB 1-receptors stimulation mimic preconditioning phenomena. Since the cardioprotective effect of cannabinoid HU-210 is occurred both in the experiments in vivo and in the experiments in vitro there are reasons to believe that the protective effect of HU-210 is me- diated via an activation of cardiac CB1-receptors. It is established that the cardioprotective effect of cannabinoid HU-2 10 is depends upon a stimulation ofprotein kinase C whereas NO-synthase is not involved in protective impact of CB1-receptor stimulation.
| Original language | English |
|---|---|
| Pages (from-to) | 909-920 |
| Number of pages | 12 |
| Journal | Rossiǐskii fiziologicheskiǐ zhurnal imeni I.M. Sechenova / Rossiǐskaia akademiia nauk |
| Volume | 101 |
| Issue number | 8 |
| Publication status | Published - 1 Aug 2015 |
ASJC Scopus subject areas
- Medicine(all)
Fingerprint Dive into the research topics of 'MIMICKING ISCHEMIC PRECONDITIONING PHENOMENON THROUGH THE IMPACT ON THE CANNABINOID RECEPTORS: ROLE OF PROTEIN KINASE AND NO-SYNTHASE'. Together they form a unique fingerprint.
Cite this
Lishmanov, Y. B., Maslov, L. N., Krylatov, A. V., & Khaliulin, I. G. (2015). MIMICKING ISCHEMIC PRECONDITIONING PHENOMENON THROUGH THE IMPACT ON THE CANNABINOID RECEPTORS: ROLE OF PROTEIN KINASE AND NO-SYNTHASE. Rossiǐskii fiziologicheskiǐ zhurnal imeni I.M. Sechenova / Rossiǐskaia akademiia nauk, 101(8), 909-920.