Abstract
It was established that CB 1-receptors stimulation mimic preconditioning phenomena. Since the cardioprotective effect of cannabinoid HU-210 is occurred both in the experiments in vivo and in the experiments in vitro there are reasons to believe that the protective effect of HU-210 is me- diated via an activation of cardiac CB1-receptors. It is established that the cardioprotective effect of cannabinoid HU-2 10 is depends upon a stimulation ofprotein kinase C whereas NO-synthase is not involved in protective impact of CB1-receptor stimulation.
| Original language | English |
|---|---|
| Pages (from-to) | 909-920 |
| Number of pages | 12 |
| Journal | Rossiǐskii fiziologicheskiǐ zhurnal imeni I.M. Sechenova / Rossiǐskaia akademiia nauk |
| Volume | 101 |
| Issue number | 8 |
| Publication status | Published - 1 Aug 2015 |
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ASJC Scopus subject areas
- Medicine(all)
Cite this
MIMICKING ISCHEMIC PRECONDITIONING PHENOMENON THROUGH THE IMPACT ON THE CANNABINOID RECEPTORS : ROLE OF PROTEIN KINASE AND NO-SYNTHASE. / Lishmanov, Yu B.; Maslov, L. N.; Krylatov, A. V.; Khaliulin, I. G.
In: Rossiǐskii fiziologicheskiǐ zhurnal imeni I.M. Sechenova / Rossiǐskaia akademiia nauk, Vol. 101, No. 8, 01.08.2015, p. 909-920.Research output: Contribution to journal › Article
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TY - JOUR
T1 - MIMICKING ISCHEMIC PRECONDITIONING PHENOMENON THROUGH THE IMPACT ON THE CANNABINOID RECEPTORS
T2 - ROLE OF PROTEIN KINASE AND NO-SYNTHASE
AU - Lishmanov, Yu B.
AU - Maslov, L. N.
AU - Krylatov, A. V.
AU - Khaliulin, I. G.
PY - 2015/8/1
Y1 - 2015/8/1
N2 - It was established that CB 1-receptors stimulation mimic preconditioning phenomena. Since the cardioprotective effect of cannabinoid HU-210 is occurred both in the experiments in vivo and in the experiments in vitro there are reasons to believe that the protective effect of HU-210 is me- diated via an activation of cardiac CB1-receptors. It is established that the cardioprotective effect of cannabinoid HU-2 10 is depends upon a stimulation ofprotein kinase C whereas NO-synthase is not involved in protective impact of CB1-receptor stimulation.
AB - It was established that CB 1-receptors stimulation mimic preconditioning phenomena. Since the cardioprotective effect of cannabinoid HU-210 is occurred both in the experiments in vivo and in the experiments in vitro there are reasons to believe that the protective effect of HU-210 is me- diated via an activation of cardiac CB1-receptors. It is established that the cardioprotective effect of cannabinoid HU-2 10 is depends upon a stimulation ofprotein kinase C whereas NO-synthase is not involved in protective impact of CB1-receptor stimulation.
UR - http://www.scopus.com/inward/record.url?scp=84952334246&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84952334246&partnerID=8YFLogxK
M3 - Article
C2 - 26591586
AN - SCOPUS:84952334246
VL - 101
SP - 909
EP - 920
JO - Fiziologicheskii Zhurnal Imeni I.M. Sechenova
JF - Fiziologicheskii Zhurnal Imeni I.M. Sechenova
SN - 0869-8139
IS - 8
ER -