Abstract
The field of material surface modification with aim of biomaterials construction involves several approaches based on surface treatments that allow to prepare materials, which support the cell adhesion and proliferation and thus aid and improve the tissue formation. Modified materials have a surface composition and morphology intended to interact with biological systems and cellular functions. Not only surface chemistry has an effect on material biological response, surface structures of different morphology can be constructed to guide a desirable biological outcome. Nano-patterned material surfaces have been tested with aim to determine how surface geometry, physical and chemical properties on a micro- and nano-scale can affect cellular response and influence cell adhesion and proliferation. Surface physico-chemical properties (e.g. chemistry, morphology, wettability, electrical conductivity, optical and mechanical properties) of treated surfaces were determined. The enhancement in cell adhesion and proliferation on modified substrates was studied in vitro. Bactericidal action of noble metal nano-particles (e.g. Au, Ag) on polymers was characterized. The influence of metal nano-particles grafting by using metal nano-particle suspension prepared by "green" methods was determined.
| Original language | English |
|---|---|
| Pages (from-to) | 1162-1168 |
| Number of pages | 7 |
| Journal | Manufacturing Technology |
| Volume | 16 |
| Issue number | 5 |
| Publication status | Published - 1 Jan 2016 |
| Externally published | Yes |
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Keywords
- Bacteria
- Cells
- Morphology
- Polymer
- Surface characterization
- Surface treatment
ASJC Scopus subject areas
- Industrial and Manufacturing Engineering
Cite this
Microscopy of material surfaces for tissue engineering. / Švorčík, Václav; Slepička, Petr; Siegel, Jakub; Lyutakov, Oleksiy; Kasálková, Nikola Slepičková; Kolářová, Kateřina; Řezníčková, Alena; Kolská, Zdeňka.
In: Manufacturing Technology, Vol. 16, No. 5, 01.01.2016, p. 1162-1168.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Microscopy of material surfaces for tissue engineering
AU - Švorčík, Václav
AU - Slepička, Petr
AU - Siegel, Jakub
AU - Lyutakov, Oleksiy
AU - Kasálková, Nikola Slepičková
AU - Kolářová, Kateřina
AU - Řezníčková, Alena
AU - Kolská, Zdeňka
PY - 2016/1/1
Y1 - 2016/1/1
N2 - The field of material surface modification with aim of biomaterials construction involves several approaches based on surface treatments that allow to prepare materials, which support the cell adhesion and proliferation and thus aid and improve the tissue formation. Modified materials have a surface composition and morphology intended to interact with biological systems and cellular functions. Not only surface chemistry has an effect on material biological response, surface structures of different morphology can be constructed to guide a desirable biological outcome. Nano-patterned material surfaces have been tested with aim to determine how surface geometry, physical and chemical properties on a micro- and nano-scale can affect cellular response and influence cell adhesion and proliferation. Surface physico-chemical properties (e.g. chemistry, morphology, wettability, electrical conductivity, optical and mechanical properties) of treated surfaces were determined. The enhancement in cell adhesion and proliferation on modified substrates was studied in vitro. Bactericidal action of noble metal nano-particles (e.g. Au, Ag) on polymers was characterized. The influence of metal nano-particles grafting by using metal nano-particle suspension prepared by "green" methods was determined.
AB - The field of material surface modification with aim of biomaterials construction involves several approaches based on surface treatments that allow to prepare materials, which support the cell adhesion and proliferation and thus aid and improve the tissue formation. Modified materials have a surface composition and morphology intended to interact with biological systems and cellular functions. Not only surface chemistry has an effect on material biological response, surface structures of different morphology can be constructed to guide a desirable biological outcome. Nano-patterned material surfaces have been tested with aim to determine how surface geometry, physical and chemical properties on a micro- and nano-scale can affect cellular response and influence cell adhesion and proliferation. Surface physico-chemical properties (e.g. chemistry, morphology, wettability, electrical conductivity, optical and mechanical properties) of treated surfaces were determined. The enhancement in cell adhesion and proliferation on modified substrates was studied in vitro. Bactericidal action of noble metal nano-particles (e.g. Au, Ag) on polymers was characterized. The influence of metal nano-particles grafting by using metal nano-particle suspension prepared by "green" methods was determined.
KW - Bacteria
KW - Cells
KW - Morphology
KW - Polymer
KW - Surface characterization
KW - Surface treatment
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UR - http://www.scopus.com/inward/citedby.url?scp=84997282835&partnerID=8YFLogxK
M3 - Article
VL - 16
SP - 1162
EP - 1168
JO - Manufacturing Technology
JF - Manufacturing Technology
SN - 1213-2489
IS - 5
ER -