Abstract
Phthalates are endocrine disruptors frequently occurring in the general and industrial environment and in many industrial products. Moreover, they are also suspected of being carcinogenic, teratogenic, and mutagenic, and they show diverse toxicity profiles depending on their structures. The European Union and the United States Environmental Protection Agency (US EPA) have included many phthalates in the list of priority substances with potential endocrine-disrupting action. They are: dimethyl phthalate (DMP), diethyl phthalate (DEP), dibutyl phthalate (DBP), butylbenzyl phthalate (BBP), diethylhexyl phthalate (DEHP), di-iso-nonyl phthalate (DINP), di-iso-decyl phthalate (DIDP), di-n-decyl phthalate (DnDP), and dioctyl phthalate (DOP). There is an ever-increasing demand for new analytical methods suitable for monitoring different phthalates in various environmental, biological, and other matrices. Separation and spectrometric methods are most frequently used. However, modern electroanalytical methods can also play a useful role in this field because of their high sensitivity, reasonable selectivity, easy automation, and miniaturization, and especially low investment and running costs, which makes them suitable for large-scale monitoring. Therefore, this review outlines possibilities and limitations of various analytical methods for determination of endocrine-disruptor phthalate esters in various matrices, including somewhat neglected electroanalytical methods.
| Original language | English |
|---|---|
| Pages (from-to) | 146-159 |
| Number of pages | 14 |
| Journal | Critical Reviews in Analytical Chemistry |
| Volume | 46 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 3 Mar 2016 |
| Externally published | Yes |
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Keywords
- Carcinogens
- endocrine disruptors
- phthalates
ASJC Scopus subject areas
- Analytical Chemistry
Cite this
Methods for the Determination of Endocrine-Disrupting Phthalate Esters. / Qureshi, Munawar Saeed; Yusoff, Abdull Rahim bin Mohd; Wirzal, Mohd Dzul Hakim; Sirajuddin, ; Barek, Jiri; Afridi, Hassan Imran; Üstündag, Zafer.
In: Critical Reviews in Analytical Chemistry, Vol. 46, No. 2, 03.03.2016, p. 146-159.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - Methods for the Determination of Endocrine-Disrupting Phthalate Esters
AU - Qureshi, Munawar Saeed
AU - Yusoff, Abdull Rahim bin Mohd
AU - Wirzal, Mohd Dzul Hakim
AU - Sirajuddin,
AU - Barek, Jiri
AU - Afridi, Hassan Imran
AU - Üstündag, Zafer
PY - 2016/3/3
Y1 - 2016/3/3
N2 - Phthalates are endocrine disruptors frequently occurring in the general and industrial environment and in many industrial products. Moreover, they are also suspected of being carcinogenic, teratogenic, and mutagenic, and they show diverse toxicity profiles depending on their structures. The European Union and the United States Environmental Protection Agency (US EPA) have included many phthalates in the list of priority substances with potential endocrine-disrupting action. They are: dimethyl phthalate (DMP), diethyl phthalate (DEP), dibutyl phthalate (DBP), butylbenzyl phthalate (BBP), diethylhexyl phthalate (DEHP), di-iso-nonyl phthalate (DINP), di-iso-decyl phthalate (DIDP), di-n-decyl phthalate (DnDP), and dioctyl phthalate (DOP). There is an ever-increasing demand for new analytical methods suitable for monitoring different phthalates in various environmental, biological, and other matrices. Separation and spectrometric methods are most frequently used. However, modern electroanalytical methods can also play a useful role in this field because of their high sensitivity, reasonable selectivity, easy automation, and miniaturization, and especially low investment and running costs, which makes them suitable for large-scale monitoring. Therefore, this review outlines possibilities and limitations of various analytical methods for determination of endocrine-disruptor phthalate esters in various matrices, including somewhat neglected electroanalytical methods.
AB - Phthalates are endocrine disruptors frequently occurring in the general and industrial environment and in many industrial products. Moreover, they are also suspected of being carcinogenic, teratogenic, and mutagenic, and they show diverse toxicity profiles depending on their structures. The European Union and the United States Environmental Protection Agency (US EPA) have included many phthalates in the list of priority substances with potential endocrine-disrupting action. They are: dimethyl phthalate (DMP), diethyl phthalate (DEP), dibutyl phthalate (DBP), butylbenzyl phthalate (BBP), diethylhexyl phthalate (DEHP), di-iso-nonyl phthalate (DINP), di-iso-decyl phthalate (DIDP), di-n-decyl phthalate (DnDP), and dioctyl phthalate (DOP). There is an ever-increasing demand for new analytical methods suitable for monitoring different phthalates in various environmental, biological, and other matrices. Separation and spectrometric methods are most frequently used. However, modern electroanalytical methods can also play a useful role in this field because of their high sensitivity, reasonable selectivity, easy automation, and miniaturization, and especially low investment and running costs, which makes them suitable for large-scale monitoring. Therefore, this review outlines possibilities and limitations of various analytical methods for determination of endocrine-disruptor phthalate esters in various matrices, including somewhat neglected electroanalytical methods.
KW - Carcinogens
KW - endocrine disruptors
KW - phthalates
UR - http://www.scopus.com/inward/record.url?scp=84962502492&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84962502492&partnerID=8YFLogxK
U2 - 10.1080/10408347.2015.1004157
DO - 10.1080/10408347.2015.1004157
M3 - Review article
VL - 46
SP - 146
EP - 159
JO - Critical Reviews in Analytical Chemistry
JF - Critical Reviews in Analytical Chemistry
SN - 1040-8347
IS - 2
ER -