Abstract
The paper focuses on research aimed at creating and testing a new approach to evaluate the processes of aggregation and sedimentation of red blood cells for purpose of its use in clinical laboratory diagnostics. The proposed method is based on photometric analysis of blood sample formed as a sessile drop. The results of clinical approbation of this method are given in the paper. Analysis of the processes occurring in the sample in the form of sessile drop during the process of blood cells sedimentation is described. The results of experimental studies to evaluate the effect of the droplet sample focusing properties on light radiation transmittance are presented. It is shown that this method significantly reduces the sample volume and provides sufficiently high sensitivity to the studied processes.
| Original language | English |
|---|---|
| Pages (from-to) | 621-630 |
| Number of pages | 10 |
| Journal | Medical and Biological Engineering and Computing |
| Volume | 55 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - 1 Apr 2017 |
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Keywords
- Aggregation
- Blood
- Erythrocyte sedimentation rate
- Photometry
ASJC Scopus subject areas
- Biomedical Engineering
- Computer Science Applications
Cite this
Method of evaluation of process of red blood cell sedimentation based on photometry of droplet samples. / Aristov, Alexander; Nosova, Ekaterina.
In: Medical and Biological Engineering and Computing, Vol. 55, No. 4, 01.04.2017, p. 621-630.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Method of evaluation of process of red blood cell sedimentation based on photometry of droplet samples
AU - Aristov, Alexander
AU - Nosova, Ekaterina
PY - 2017/4/1
Y1 - 2017/4/1
N2 - The paper focuses on research aimed at creating and testing a new approach to evaluate the processes of aggregation and sedimentation of red blood cells for purpose of its use in clinical laboratory diagnostics. The proposed method is based on photometric analysis of blood sample formed as a sessile drop. The results of clinical approbation of this method are given in the paper. Analysis of the processes occurring in the sample in the form of sessile drop during the process of blood cells sedimentation is described. The results of experimental studies to evaluate the effect of the droplet sample focusing properties on light radiation transmittance are presented. It is shown that this method significantly reduces the sample volume and provides sufficiently high sensitivity to the studied processes.
AB - The paper focuses on research aimed at creating and testing a new approach to evaluate the processes of aggregation and sedimentation of red blood cells for purpose of its use in clinical laboratory diagnostics. The proposed method is based on photometric analysis of blood sample formed as a sessile drop. The results of clinical approbation of this method are given in the paper. Analysis of the processes occurring in the sample in the form of sessile drop during the process of blood cells sedimentation is described. The results of experimental studies to evaluate the effect of the droplet sample focusing properties on light radiation transmittance are presented. It is shown that this method significantly reduces the sample volume and provides sufficiently high sensitivity to the studied processes.
KW - Aggregation
KW - Blood
KW - Erythrocyte sedimentation rate
KW - Photometry
UR - http://www.scopus.com/inward/record.url?scp=84978110473&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84978110473&partnerID=8YFLogxK
U2 - 10.1007/s11517-016-1542-5
DO - 10.1007/s11517-016-1542-5
M3 - Article
VL - 55
SP - 621
EP - 630
JO - Medical and Biological Engineering and Computing
JF - Medical and Biological Engineering and Computing
SN - 0140-0118
IS - 4
ER -