Metal organic frameworks mimicking natural enzymes: A structural and functional analogy

Ipsita Nath, Jeet Chakraborty, Francis Walter Cornelius Verpoort

Research output: Contribution to journalReview article

124 Citations (Scopus)

Abstract

In this review, we have portrayed the structure, synthesis and applications of a variety of biomimetic MOFs from an unprecedented angle. Synthetic MOF analogues of five distinct enzymes: phosphotriesterase, hydrogenase, cytochrome P450, chymotrypsin and carbonic anhydrase, have been discussed with their skeletal comparison to actual enzymatic active sites as reference, and an explanation of catalytic pathways from the mechanistic cycle of the corresponding enzymes is depicted. We demonstrated critically each of the five discrete situations by assimilating available benchmark researches in an attempt to provide a concise literature source on the ingenious design strategies and versatile biomimetic applications of this domain of materials.

Original languageEnglish
Pages (from-to)4127-4170
Number of pages44
JournalChemical Society Reviews
Volume45
Issue number15
DOIs
Publication statusPublished - 7 Aug 2016
Externally publishedYes

Fingerprint

Biomimetics
Phosphoric Triester Hydrolases
Metals
Hydrogenase
Carbonic Anhydrases
Chymotrypsin
Enzymes
Cytochrome P-450 Enzyme System

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Metal organic frameworks mimicking natural enzymes : A structural and functional analogy. / Nath, Ipsita; Chakraborty, Jeet; Verpoort, Francis Walter Cornelius.

In: Chemical Society Reviews, Vol. 45, No. 15, 07.08.2016, p. 4127-4170.

Research output: Contribution to journalReview article

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