Mechanisms responsible for the resistance of tracheal smooth muscle to histamine in rats

L. V. Kapilevich, M. B. Baskakov, M. A. Medvedev, M. V. Kuskov, I. V. Kovalev, E. Yu Petrov

Research output: Contribution to journalArticlepeer-review

Abstract

A mechanographic study of contractile responses by tracheal smooth muscle segments of rats to a histaminergic agent showed that intact segments did not respond to histamine in the concentrations used (0.01–10 μM), whereas depolarized segments responded to histamine by dose-dependent contraction which were considerably enhanced following mechanical removal of the tracheal epithelium.

Original languageEnglish
Pages (from-to)903-904
Number of pages2
JournalBulletin of Experimental Biology and Medicine
Volume120
Issue number3
DOIs
Publication statusPublished - Sep 1995

Keywords

  • histamine
  • smooth muscle
  • trachea

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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