Local hyperthermia in treatment for malignant brain tumors

A. I. Ryabova, O. V. Gribova, V. A. Novikov, E. L. Choinzonov, Zh A. Startseva, I. A. Miloichikova, N. D. Turgunova, R. V. Vasiliev

Research output: Contribution to journalReview articlepeer-review

Abstract

Unsatisfactory results of complex treatment for malignant brain tumors stimulate search of new effective methods of treatment. Radiation therapy is an integral part of the combined treatment but often does not influence lethally on resistant tumor cells. Thereby in recent decades there has been an active search for different modifiers, which can increase the sensitivity of tumors to chemotherapy and radiotherapy. One of the universal sensitizers is the local hyperthermia. Experimental data showed that the effect of high temperatures had both a direct damaging effect on tumor cells and a sensitizing effect. The literature review given in the article provides an overview of the existing methods of the local hyperthermia for brain tumors treatment.

Original languageEnglish
Pages (from-to)54-61
Number of pages8
JournalVoprosy Onkologii
Volume64
Issue number1
Publication statusPublished - 2018

Keywords

  • Combined treatment
  • Local hyperthermia
  • Malignant brain tumors

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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