Ligands of opioid receptors and sigma receptors and the correction of heart electrical instability in postinfarction cardiosclerosis

L. N. Maslov, Yu B. Lishmanov, N. V. Naryzhnaya, A. V. Krylatov, S. W. Tam

Research output: Contribution to journalArticle

Abstract

Peripheral administration of the μ-or κ-receptor agonists or σ-receptor antagonists produced a significant receptor-dependent increase in the ventricular fibrillation threshold in rats with postinfarction cardiosclerosis. The effect was not observed u̇pon administration of the ε-receptor agonist β-endorphin. The receptor and molecular mechanisms of the observed effects are discussed.

Original languageEnglish
Pages (from-to)41
Number of pages1
JournalEksperimental'naya i Klinicheskaya Farmakologiya
Volume64
Issue number1
Publication statusPublished - 2001

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sigma Receptors
Opioid Receptors
Ventricular Fibrillation
Ligands
Endorphins
Rats

ASJC Scopus subject areas

  • Pharmacology, Toxicology and Pharmaceutics(all)

Cite this

Ligands of opioid receptors and sigma receptors and the correction of heart electrical instability in postinfarction cardiosclerosis. / Maslov, L. N.; Lishmanov, Yu B.; Naryzhnaya, N. V.; Krylatov, A. V.; Tam, S. W.

In: Eksperimental'naya i Klinicheskaya Farmakologiya, Vol. 64, No. 1, 2001, p. 41.

Research output: Contribution to journalArticle

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