Abstract
We measured the concentrations of IL-6 and IL-15 in blood plasma of mice at different terms after forced swimming, taking into account exercise intensity and preliminary training. It was shown that training was an important factor affecting blood plasma level of IL both at rest and after single forced swimming: in trained animals, the concentration of both myokines increased immediately after swimming, while in untrained animals, this increase was observed only after 5 h. Changes in cytokine production against the background of training can be associated with various factors, including neuroendocrine mechanisms, stress, modification of intracellular signaling, as well as reorganization of transcriptional mechanisms in muscle fibers. The most important factor is shift in the ratio of monovalent cations (sodium and potassium) in the cytoplasm.
| Original language | English |
|---|---|
| Pages (from-to) | 1-4 |
| Number of pages | 4 |
| Journal | Bulletin of Experimental Biology and Medicine |
| DOIs | |
| Publication status | Accepted/In press - 3 Jun 2017 |
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ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
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Level of Interleukins IL-6 and IL-15 in Blood Plasma of Mice after Forced Swimming Test. / Kapilevich, L. V.; Kironenko, T. A.; Zakharova, A. N.; Kabachkova, A. V.; Orlov, S. N.
In: Bulletin of Experimental Biology and Medicine, 03.06.2017, p. 1-4.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Level of Interleukins IL-6 and IL-15 in Blood Plasma of Mice after Forced Swimming Test
AU - Kapilevich, L. V.
AU - Kironenko, T. A.
AU - Zakharova, A. N.
AU - Kabachkova, A. V.
AU - Orlov, S. N.
PY - 2017/6/3
Y1 - 2017/6/3
N2 - We measured the concentrations of IL-6 and IL-15 in blood plasma of mice at different terms after forced swimming, taking into account exercise intensity and preliminary training. It was shown that training was an important factor affecting blood plasma level of IL both at rest and after single forced swimming: in trained animals, the concentration of both myokines increased immediately after swimming, while in untrained animals, this increase was observed only after 5 h. Changes in cytokine production against the background of training can be associated with various factors, including neuroendocrine mechanisms, stress, modification of intracellular signaling, as well as reorganization of transcriptional mechanisms in muscle fibers. The most important factor is shift in the ratio of monovalent cations (sodium and potassium) in the cytoplasm.
AB - We measured the concentrations of IL-6 and IL-15 in blood plasma of mice at different terms after forced swimming, taking into account exercise intensity and preliminary training. It was shown that training was an important factor affecting blood plasma level of IL both at rest and after single forced swimming: in trained animals, the concentration of both myokines increased immediately after swimming, while in untrained animals, this increase was observed only after 5 h. Changes in cytokine production against the background of training can be associated with various factors, including neuroendocrine mechanisms, stress, modification of intracellular signaling, as well as reorganization of transcriptional mechanisms in muscle fibers. The most important factor is shift in the ratio of monovalent cations (sodium and potassium) in the cytoplasm.
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UR - http://www.scopus.com/inward/citedby.url?scp=85020095094&partnerID=8YFLogxK
U2 - 10.1007/s10517-017-3725-y
DO - 10.1007/s10517-017-3725-y
M3 - Article
AN - SCOPUS:85020095094
SP - 1
EP - 4
JO - Bulletin of Experimental Biology and Medicine
JF - Bulletin of Experimental Biology and Medicine
SN - 0007-4888
ER -