Lectin-based nanoagents for specific cell labelling and optical visualization

V. O. Shipunova, M. P. Nikitin, P. I. Nikitin, S. M. Deyev

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Interactions between lectin-modified nanoparticles and various glycoproteins were investigated for development of effective nanoagents for therapy and diagnostics. We screened a variety of lectin-glycoprotein pairs both in cell-free mode and in vitro in human cell culture to create a number of highly specific nanoparticle-lectin conjugates. We showed that the obtained conjugates can be successfully used as biomarker-specific agents for specific cell visualization in biomedical diagnostics.

Original languageEnglish
Title of host publicationProceedings - 2016 International Conference Laser Optics, LO 2016
PublisherInstitute of Electrical and Electronics Engineers Inc.
PagesS237
ISBN (Electronic)9781467397353
DOIs
Publication statusPublished - 23 Aug 2016
Externally publishedYes
Event2016 International Conference Laser Optics, LO 2016 - St. Petersburg, Russian Federation
Duration: 27 Jun 20161 Jul 2016

Conference

Conference2016 International Conference Laser Optics, LO 2016
CountryRussian Federation
CitySt. Petersburg
Period27.6.161.7.16

Fingerprint

Lectins
Labeling
marking
Glycoproteins
Visualization
nanoparticles
biomarkers
cells
Nanoparticles
therapy
Biomarkers
Cell culture
interactions

Keywords

  • biomedical optical imaging
  • cancer cells
  • lectins
  • nanoparticles
  • theranostics

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics

Cite this

Shipunova, V. O., Nikitin, M. P., Nikitin, P. I., & Deyev, S. M. (2016). Lectin-based nanoagents for specific cell labelling and optical visualization. In Proceedings - 2016 International Conference Laser Optics, LO 2016 (pp. S237). [7550004] Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/LO.2016.7550004

Lectin-based nanoagents for specific cell labelling and optical visualization. / Shipunova, V. O.; Nikitin, M. P.; Nikitin, P. I.; Deyev, S. M.

Proceedings - 2016 International Conference Laser Optics, LO 2016. Institute of Electrical and Electronics Engineers Inc., 2016. p. S237 7550004.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Shipunova, VO, Nikitin, MP, Nikitin, PI & Deyev, SM 2016, Lectin-based nanoagents for specific cell labelling and optical visualization. in Proceedings - 2016 International Conference Laser Optics, LO 2016., 7550004, Institute of Electrical and Electronics Engineers Inc., pp. S237, 2016 International Conference Laser Optics, LO 2016, St. Petersburg, Russian Federation, 27.6.16. https://doi.org/10.1109/LO.2016.7550004
Shipunova VO, Nikitin MP, Nikitin PI, Deyev SM. Lectin-based nanoagents for specific cell labelling and optical visualization. In Proceedings - 2016 International Conference Laser Optics, LO 2016. Institute of Electrical and Electronics Engineers Inc. 2016. p. S237. 7550004 https://doi.org/10.1109/LO.2016.7550004
Shipunova, V. O. ; Nikitin, M. P. ; Nikitin, P. I. ; Deyev, S. M. / Lectin-based nanoagents for specific cell labelling and optical visualization. Proceedings - 2016 International Conference Laser Optics, LO 2016. Institute of Electrical and Electronics Engineers Inc., 2016. pp. S237
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