Abstract
Interactions between lectin-modified nanoparticles and various glycoproteins were investigated for development of effective nanoagents for therapy and diagnostics. We screened a variety of lectin-glycoprotein pairs both in cell-free mode and in vitro in human cell culture to create a number of highly specific nanoparticle-lectin conjugates. We showed that the obtained conjugates can be successfully used as biomarker-specific agents for specific cell visualization in biomedical diagnostics.
Original language | English |
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Title of host publication | Proceedings - 2016 International Conference Laser Optics, LO 2016 |
Publisher | Institute of Electrical and Electronics Engineers Inc. |
Pages | S237 |
ISBN (Electronic) | 9781467397353 |
DOIs | |
Publication status | Published - 23 Aug 2016 |
Externally published | Yes |
Event | 2016 International Conference Laser Optics, LO 2016 - St. Petersburg, Russian Federation Duration: 27 Jun 2016 → 1 Jul 2016 |
Conference
Conference | 2016 International Conference Laser Optics, LO 2016 |
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Country | Russian Federation |
City | St. Petersburg |
Period | 27.6.16 → 1.7.16 |
Keywords
- biomedical optical imaging
- cancer cells
- lectins
- nanoparticles
- theranostics
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Atomic and Molecular Physics, and Optics