Abstract
Interactions between lectin-modified nanoparticles and various glycoproteins were investigated for development of effective nanoagents for therapy and diagnostics. We screened a variety of lectin-glycoprotein pairs both in cell-free mode and in vitro in human cell culture to create a number of highly specific nanoparticle-lectin conjugates. We showed that the obtained conjugates can be successfully used as biomarker-specific agents for specific cell visualization in biomedical diagnostics.
| Original language | English |
|---|---|
| Title of host publication | Proceedings - 2016 International Conference Laser Optics, LO 2016 |
| Publisher | Institute of Electrical and Electronics Engineers Inc. |
| Pages | S237 |
| ISBN (Electronic) | 9781467397353 |
| DOIs | |
| Publication status | Published - 23 Aug 2016 |
| Externally published | Yes |
| Event | 2016 International Conference Laser Optics, LO 2016 - St. Petersburg, Russian Federation Duration: 27 Jun 2016 → 1 Jul 2016 |
Conference
| Conference | 2016 International Conference Laser Optics, LO 2016 |
|---|---|
| Country | Russian Federation |
| City | St. Petersburg |
| Period | 27.6.16 → 1.7.16 |
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Keywords
- biomedical optical imaging
- cancer cells
- lectins
- nanoparticles
- theranostics
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Atomic and Molecular Physics, and Optics
Cite this
Lectin-based nanoagents for specific cell labelling and optical visualization. / Shipunova, V. O.; Nikitin, M. P.; Nikitin, P. I.; Deyev, S. M.
Proceedings - 2016 International Conference Laser Optics, LO 2016. Institute of Electrical and Electronics Engineers Inc., 2016. p. S237 7550004.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - Lectin-based nanoagents for specific cell labelling and optical visualization
AU - Shipunova, V. O.
AU - Nikitin, M. P.
AU - Nikitin, P. I.
AU - Deyev, S. M.
PY - 2016/8/23
Y1 - 2016/8/23
N2 - Interactions between lectin-modified nanoparticles and various glycoproteins were investigated for development of effective nanoagents for therapy and diagnostics. We screened a variety of lectin-glycoprotein pairs both in cell-free mode and in vitro in human cell culture to create a number of highly specific nanoparticle-lectin conjugates. We showed that the obtained conjugates can be successfully used as biomarker-specific agents for specific cell visualization in biomedical diagnostics.
AB - Interactions between lectin-modified nanoparticles and various glycoproteins were investigated for development of effective nanoagents for therapy and diagnostics. We screened a variety of lectin-glycoprotein pairs both in cell-free mode and in vitro in human cell culture to create a number of highly specific nanoparticle-lectin conjugates. We showed that the obtained conjugates can be successfully used as biomarker-specific agents for specific cell visualization in biomedical diagnostics.
KW - biomedical optical imaging
KW - cancer cells
KW - lectins
KW - nanoparticles
KW - theranostics
UR - http://www.scopus.com/inward/record.url?scp=84987851097&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84987851097&partnerID=8YFLogxK
U2 - 10.1109/LO.2016.7550004
DO - 10.1109/LO.2016.7550004
M3 - Conference contribution
AN - SCOPUS:84987851097
SP - S237
BT - Proceedings - 2016 International Conference Laser Optics, LO 2016
PB - Institute of Electrical and Electronics Engineers Inc.
ER -