Lectin-based nanoagents for specific cell labelling and optical visualization

Abstract

Interactions between lectin-modified nanoparticles and various glycoproteins were investigated for development of effective nanoagents for therapy and diagnostics. We screened a variety of lectin-glycoprotein pairs both in cell-free mode and in vitro in human cell culture to create a number of highly specific nanoparticle-lectin conjugates. We showed that the obtained conjugates can be successfully used as biomarker-specific agents for specific cell visualization in biomedical diagnostics.

Original language	English
Title of host publication	Proceedings - 2016 International Conference Laser Optics, LO 2016
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	S237
ISBN (Electronic)	9781467397353
DOIs	https://doi.org/10.1109/LO.2016.7550004
Publication status	Published - 23 Aug 2016
Externally published	Yes
Event	2016 International Conference Laser Optics, LO 2016 - St. Petersburg, Russian Federation Duration: 27 Jun 2016 → 1 Jul 2016

Conference

Conference	2016 International Conference Laser Optics, LO 2016
Country	Russian Federation
City	St. Petersburg
Period	27.6.16 → 1.7.16

Keywords

biomedical optical imaging
cancer cells
lectins
nanoparticles
theranostics

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Atomic and Molecular Physics, and Optics

Access to Document

10.1109/LO.2016.7550004

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Cite this

Lectin-based nanoagents for specific cell labelling and optical visualization. / Shipunova, V. O.; Nikitin, M. P.; Nikitin, P. I.; Deyev, S. M.

Proceedings - 2016 International Conference Laser Optics, LO 2016. Institute of Electrical and Electronics Engineers Inc., 2016. p. S237 7550004.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Shipunova, VO, Nikitin, MP, Nikitin, PI & Deyev, SM 2016, Lectin-based nanoagents for specific cell labelling and optical visualization. in Proceedings - 2016 International Conference Laser Optics, LO 2016., 7550004, Institute of Electrical and Electronics Engineers Inc., pp. S237, 2016 International Conference Laser Optics, LO 2016, St. Petersburg, Russian Federation, 27.6.16. https://doi.org/10.1109/LO.2016.7550004

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