Lectin-based nanoagents for specific cell labelling and optical visualization

V. O. Shipunova, M. P. Nikitin, P. I. Nikitin, S. M. Deyev

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Interactions between lectin-modified nanoparticles and various glycoproteins were investigated for development of effective nanoagents for therapy and diagnostics. We screened a variety of lectin-glycoprotein pairs both in cell-free mode and in vitro in human cell culture to create a number of highly specific nanoparticle-lectin conjugates. We showed that the obtained conjugates can be successfully used as biomarker-specific agents for specific cell visualization in biomedical diagnostics.

Original languageEnglish
Title of host publicationProceedings - 2016 International Conference Laser Optics, LO 2016
PublisherInstitute of Electrical and Electronics Engineers Inc.
PagesS237
ISBN (Electronic)9781467397353
DOIs
Publication statusPublished - 23 Aug 2016
Externally publishedYes
Event2016 International Conference Laser Optics, LO 2016 - St. Petersburg, Russian Federation
Duration: 27 Jun 20161 Jul 2016

Conference

Conference2016 International Conference Laser Optics, LO 2016
CountryRussian Federation
CitySt. Petersburg
Period27.6.161.7.16

Keywords

  • biomedical optical imaging
  • cancer cells
  • lectins
  • nanoparticles
  • theranostics

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics

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  • Cite this

    Shipunova, V. O., Nikitin, M. P., Nikitin, P. I., & Deyev, S. M. (2016). Lectin-based nanoagents for specific cell labelling and optical visualization. In Proceedings - 2016 International Conference Laser Optics, LO 2016 (pp. S237). [7550004] Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/LO.2016.7550004