Layer by layer microencapsulate technology as basis for fabrication of drug delivery nanosystems with remote controlling properties

Olga A. Inozemtseva, Sergey A. Portnov, Tatyana A. Kolesnikova, Dmitry A. Gorin, Gleb B. Sukhorukov

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

New class of microobjects synthesized by Layer-by-Layer assembly method has been observed. These are polyelectrolyte nanocomposite microcapsules. The influence of microenvironment parameters (pH and ionic force of a solution, structure of solvent and temperature) on the physical and chemical properties of polyelectrolyte capsules has been described. The basic approaches to capsulation of organic substances, based on the change of microcapsule environment properties, the approaches to modification of microcapsule shells to give them sensitivity to external influences have been observed and analyzed. Usually the inorganic nanoparticles are used for such modification of microcontainers. During our work the basic methods of nanocomposite capsules fabrication were described and the ways of microcapsule shell permeability control by external influences, such as electromagnetic irradiation and ultrasound were considered.

Original languageEnglish
Title of host publicationHandbook of Materials for Nanomedicine
PublisherPan Stanford Publishing Pte. Ltd.
Pages131-167
Number of pages37
ISBN (Print)9789814267557
DOIs
Publication statusPublished - 1 Sep 2010
Externally publishedYes

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Nanosystems
Polyelectrolytes
Drug delivery
Nanocomposites
Fabrication
Chemical properties
Physical properties
Ultrasonics
Irradiation
Nanoparticles
Temperature

ASJC Scopus subject areas

  • Engineering(all)

Cite this

Inozemtseva, O. A., Portnov, S. A., Kolesnikova, T. A., Gorin, D. A., & Sukhorukov, G. B. (2010). Layer by layer microencapsulate technology as basis for fabrication of drug delivery nanosystems with remote controlling properties. In Handbook of Materials for Nanomedicine (pp. 131-167). Pan Stanford Publishing Pte. Ltd.. https://doi.org/10.4032/9789814267588

Layer by layer microencapsulate technology as basis for fabrication of drug delivery nanosystems with remote controlling properties. / Inozemtseva, Olga A.; Portnov, Sergey A.; Kolesnikova, Tatyana A.; Gorin, Dmitry A.; Sukhorukov, Gleb B.

Handbook of Materials for Nanomedicine. Pan Stanford Publishing Pte. Ltd., 2010. p. 131-167.

Research output: Chapter in Book/Report/Conference proceedingChapter

Inozemtseva, OA, Portnov, SA, Kolesnikova, TA, Gorin, DA & Sukhorukov, GB 2010, Layer by layer microencapsulate technology as basis for fabrication of drug delivery nanosystems with remote controlling properties. in Handbook of Materials for Nanomedicine. Pan Stanford Publishing Pte. Ltd., pp. 131-167. https://doi.org/10.4032/9789814267588
Inozemtseva OA, Portnov SA, Kolesnikova TA, Gorin DA, Sukhorukov GB. Layer by layer microencapsulate technology as basis for fabrication of drug delivery nanosystems with remote controlling properties. In Handbook of Materials for Nanomedicine. Pan Stanford Publishing Pte. Ltd. 2010. p. 131-167 https://doi.org/10.4032/9789814267588
Inozemtseva, Olga A. ; Portnov, Sergey A. ; Kolesnikova, Tatyana A. ; Gorin, Dmitry A. ; Sukhorukov, Gleb B. / Layer by layer microencapsulate technology as basis for fabrication of drug delivery nanosystems with remote controlling properties. Handbook of Materials for Nanomedicine. Pan Stanford Publishing Pte. Ltd., 2010. pp. 131-167
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