Abstract
A study was conducted to demonstrate the application of lanthanide paramagnetic probes for nuclear magnetic resonance spectroscopic studies of molecular conformational dynamics in solution to macrocyclic molecules. It was found that lanthanide complexes in solution exhibited a well-defined luminescence, which was characterized by narrow emission bands, large Stokes' shifts, and long excited-state lifetimes. A number of NMR investigations of intramolecular dynamics for lanthanide complexes in aqueous solutions, with other macrocyclic ligands were also considered for comparison. The methodology of paramagnetic Ce, Nd, Pr, Eu, Dy, and Yb probe applications for studying the enthalpy and entropy changes in chemical exchange processes was also investigated. The advantages of the methodology in comparison with DNMR studies of diamagnetic substances were also demonstrated.
| Original language | English |
|---|---|
| Pages (from-to) | 1-21 |
| Number of pages | 21 |
| Journal | Progress in Nuclear Magnetic Resonance Spectroscopy |
| Volume | 52 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 30 Jan 2008 |
| Externally published | Yes |
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Keywords
- DOTA-like ligands
- Dynamic NMR spectroscopy
- Lanthanide-induced shifts
- Lanthanides
- Macrocyclic polyethers
- NMR lineshape
- Nuclear Overhauser effect
- Porphyrins
- Selective magnetization transfer
- Spin saturation transfer
- Spin-lattice relaxation
ASJC Scopus subject areas
- Spectroscopy
- Radiology Nuclear Medicine and imaging
- Condensed Matter Physics
Cite this
Lanthanide paramagnetic probes for NMR spectroscopic studies of molecular conformational dynamics in solution : Applications to macrocyclic molecules. / Babailov, S. P.
In: Progress in Nuclear Magnetic Resonance Spectroscopy, Vol. 52, No. 1, 30.01.2008, p. 1-21.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - Lanthanide paramagnetic probes for NMR spectroscopic studies of molecular conformational dynamics in solution
T2 - Applications to macrocyclic molecules
AU - Babailov, S. P.
PY - 2008/1/30
Y1 - 2008/1/30
N2 - A study was conducted to demonstrate the application of lanthanide paramagnetic probes for nuclear magnetic resonance spectroscopic studies of molecular conformational dynamics in solution to macrocyclic molecules. It was found that lanthanide complexes in solution exhibited a well-defined luminescence, which was characterized by narrow emission bands, large Stokes' shifts, and long excited-state lifetimes. A number of NMR investigations of intramolecular dynamics for lanthanide complexes in aqueous solutions, with other macrocyclic ligands were also considered for comparison. The methodology of paramagnetic Ce, Nd, Pr, Eu, Dy, and Yb probe applications for studying the enthalpy and entropy changes in chemical exchange processes was also investigated. The advantages of the methodology in comparison with DNMR studies of diamagnetic substances were also demonstrated.
AB - A study was conducted to demonstrate the application of lanthanide paramagnetic probes for nuclear magnetic resonance spectroscopic studies of molecular conformational dynamics in solution to macrocyclic molecules. It was found that lanthanide complexes in solution exhibited a well-defined luminescence, which was characterized by narrow emission bands, large Stokes' shifts, and long excited-state lifetimes. A number of NMR investigations of intramolecular dynamics for lanthanide complexes in aqueous solutions, with other macrocyclic ligands were also considered for comparison. The methodology of paramagnetic Ce, Nd, Pr, Eu, Dy, and Yb probe applications for studying the enthalpy and entropy changes in chemical exchange processes was also investigated. The advantages of the methodology in comparison with DNMR studies of diamagnetic substances were also demonstrated.
KW - DOTA-like ligands
KW - Dynamic NMR spectroscopy
KW - Lanthanide-induced shifts
KW - Lanthanides
KW - Macrocyclic polyethers
KW - NMR lineshape
KW - Nuclear Overhauser effect
KW - Porphyrins
KW - Selective magnetization transfer
KW - Spin saturation transfer
KW - Spin-lattice relaxation
UR - http://www.scopus.com/inward/record.url?scp=37849045887&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=37849045887&partnerID=8YFLogxK
U2 - 10.1016/j.pnmrs.2007.04.002
DO - 10.1016/j.pnmrs.2007.04.002
M3 - Review article
AN - SCOPUS:37849045887
VL - 52
SP - 1
EP - 21
JO - Progress in Nuclear Magnetic Resonance Spectroscopy
JF - Progress in Nuclear Magnetic Resonance Spectroscopy
SN - 0079-6565
IS - 1
ER -