Iodination of aryl amines in a water-paste form via stable aryl diazonium tosylates

Dmitry A. Gorlushko, Victor D. Filimonov, Elena A. Krasnokutskaya, Nadya I. Semenischeva, Bong Seong Go, Ho Yun Hwang, Eun Hye Cha, Ki Whan Chi

Research output: Contribution to journalArticle

48 Citations (Scopus)

Abstract

The diazotization of aryl amines at room temperature in paste form with NaNO2, p-TsOH and a small amount of water, followed by treatment with KI provides a new, simple, and effective route for the preparation of various aryl iodides. The water-paste and strong acid-free reaction conditions are environmentally friendly and compatible with acid-sensitive functional groups.

Original languageEnglish
Pages (from-to)1080-1082
Number of pages3
JournalTetrahedron Letters
Volume49
Issue number6
DOIs
Publication statusPublished - 4 Feb 2008

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Halogenation
Ointments
Amines
Acids
Water
Water Purification
Iodides
Functional groups
Temperature

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

Iodination of aryl amines in a water-paste form via stable aryl diazonium tosylates. / Gorlushko, Dmitry A.; Filimonov, Victor D.; Krasnokutskaya, Elena A.; Semenischeva, Nadya I.; Go, Bong Seong; Hwang, Ho Yun; Cha, Eun Hye; Chi, Ki Whan.

In: Tetrahedron Letters, Vol. 49, No. 6, 04.02.2008, p. 1080-1082.

Research output: Contribution to journalArticle

Gorlushko, Dmitry A. ; Filimonov, Victor D. ; Krasnokutskaya, Elena A. ; Semenischeva, Nadya I. ; Go, Bong Seong ; Hwang, Ho Yun ; Cha, Eun Hye ; Chi, Ki Whan. / Iodination of aryl amines in a water-paste form via stable aryl diazonium tosylates. In: Tetrahedron Letters. 2008 ; Vol. 49, No. 6. pp. 1080-1082.
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AU - Semenischeva, Nadya I.

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AU - Cha, Eun Hye

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