Intermittent versus constant aerobic exercise in middle-aged males

acute effects on arterial stiffness and factors influencing the changes

D. Peres, L. Mourot, A. Ménétrier, M. Bouhaddi, B. Degano, J. Regnard, N. Tordi

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Purpose: Both constant and intermittent acute aerobic exercises have been found to decrease arterial stiffness. However, direct comparisons of these two types of exercise are sparse. It is not known which type of exercise has the greatest effect. Methods: We evaluated the haemodynamic responses in 15 males (age 48.5 ± 1.3 years; BMI 27.5 ± 0.8 kg m−2) following acute constant (CE) and intermittent cycling exercise (IE). Duration and heart rate were matched during both exercises (131.8 ± 3.2 bpm for CE and 132.0 ± 3.1 bpm for IE). Central and peripheral arterial stiffness was assessed through pulse wave velocity (PWV). Plasma concentrations of nitric oxide (NO), atrial natriuretic peptide (ANP), blood lactate, noradrenaline, and adrenaline were measured before and after each exercise. Results: Central (+ 1.8 ± 7.4 and − 6.5 ± 6.8% for CE and IE) and upper limb PWV (+ 2.7 ± 6.2 and − 8 ± 4.6% for CE and IE) were not significantly altered although a small decrease (small effect size) was observed after IE. However, lower limb PWV significantly decreased after exercises (− 7.3 ± 5.7 and − 15.9 ± 4% after CE and IE), with a larger effect after IE. Conclusions: Greater decrease in lower limb PWV occurred after IE despite greater heart rate. This may be due to the higher blood levels of lactate during IE, while NO, ANP, noradrenaline, and adrenaline levels remained not statistically different from CE. These results underlined the importance of lactate in triggering the post-exercise vascular response to exercise, as well as its regional characteristic.

Original languageEnglish
Pages (from-to)1625-1633
Number of pages9
JournalEuropean Journal of Applied Physiology
Volume118
Issue number8
DOIs
Publication statusPublished - 1 Aug 2018

Fingerprint

Pulse Wave Analysis
Vascular Stiffness
Exercise
Lactic Acid
Atrial Natriuretic Factor
Epinephrine
Lower Extremity
Norepinephrine
Nitric Oxide
Heart Rate
Upper Extremity
Blood Vessels
Hemodynamics

Keywords

  • Acute exercise
  • Aerobic exercises
  • Middle-age
  • Nitric oxide
  • Pulse wave velocity
  • Vasodilator

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine
  • Public Health, Environmental and Occupational Health
  • Physiology (medical)

Cite this

Intermittent versus constant aerobic exercise in middle-aged males : acute effects on arterial stiffness and factors influencing the changes. / Peres, D.; Mourot, L.; Ménétrier, A.; Bouhaddi, M.; Degano, B.; Regnard, J.; Tordi, N.

In: European Journal of Applied Physiology, Vol. 118, No. 8, 01.08.2018, p. 1625-1633.

Research output: Contribution to journalArticle

Peres, D. ; Mourot, L. ; Ménétrier, A. ; Bouhaddi, M. ; Degano, B. ; Regnard, J. ; Tordi, N. / Intermittent versus constant aerobic exercise in middle-aged males : acute effects on arterial stiffness and factors influencing the changes. In: European Journal of Applied Physiology. 2018 ; Vol. 118, No. 8. pp. 1625-1633.
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AU - Peres, D.

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AU - Bouhaddi, M.

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AU - Regnard, J.

AU - Tordi, N.

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AB - Purpose: Both constant and intermittent acute aerobic exercises have been found to decrease arterial stiffness. However, direct comparisons of these two types of exercise are sparse. It is not known which type of exercise has the greatest effect. Methods: We evaluated the haemodynamic responses in 15 males (age 48.5 ± 1.3 years; BMI 27.5 ± 0.8 kg m−2) following acute constant (CE) and intermittent cycling exercise (IE). Duration and heart rate were matched during both exercises (131.8 ± 3.2 bpm for CE and 132.0 ± 3.1 bpm for IE). Central and peripheral arterial stiffness was assessed through pulse wave velocity (PWV). Plasma concentrations of nitric oxide (NO), atrial natriuretic peptide (ANP), blood lactate, noradrenaline, and adrenaline were measured before and after each exercise. Results: Central (+ 1.8 ± 7.4 and − 6.5 ± 6.8% for CE and IE) and upper limb PWV (+ 2.7 ± 6.2 and − 8 ± 4.6% for CE and IE) were not significantly altered although a small decrease (small effect size) was observed after IE. However, lower limb PWV significantly decreased after exercises (− 7.3 ± 5.7 and − 15.9 ± 4% after CE and IE), with a larger effect after IE. Conclusions: Greater decrease in lower limb PWV occurred after IE despite greater heart rate. This may be due to the higher blood levels of lactate during IE, while NO, ANP, noradrenaline, and adrenaline levels remained not statistically different from CE. These results underlined the importance of lactate in triggering the post-exercise vascular response to exercise, as well as its regional characteristic.

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KW - Pulse wave velocity

KW - Vasodilator

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