Interaction of tin(II) and arsenic(III) with DNA at the nanostructure film modified electrodes

Adriana Ferancová, Miriam Adamovski, Peter Gründler, Jiří Zima, Jiří Barek, Jürgen Mattusch, Rainer Wennrich, Ján Labuda

Research output: Contribution to journalArticle

42 Citations (Scopus)

Abstract

Biosensors based on DNA and DNA-carbon nanotubes film immobilized at the surface of a screen-printed carbon electrode were used for simple in vitro tests of chemical toxicity. The damage to DNA caused by tin(II) and arsenic(III) compounds as components of specific reaction media was evaluated by means of an electrochemical DNA marker, [Co(phen)3]3+, as the portion of original dsDNA which survives an incubation of the biosensor in the cleavage medium. The results were confirmed by the electrically heated electrode and by the measurement of the DNA guanine moiety signal.

Original languageEnglish
Pages (from-to)33-37
Number of pages5
JournalBioelectrochemistry
Volume71
Issue number1
DOIs
Publication statusPublished - 1 Sep 2007
Externally publishedYes

Fingerprint

Tin
Nanostructures
Arsenic
arsenic
tin
Electrodes
DNA
deoxyribonucleic acid
Biosensing Techniques
electrodes
Arsenicals
Toxicity Tests
Carbon Nanotubes
bioinstrumentation
Biosensors
Guanine
interactions
Genetic Markers
DNA Damage
Carbon

Keywords

  • Arsenic
  • DNA biosensor
  • DNA damage
  • Tin
  • Voltammetry

ASJC Scopus subject areas

  • Biophysics
  • Electrochemistry
  • Physical and Theoretical Chemistry

Cite this

Interaction of tin(II) and arsenic(III) with DNA at the nanostructure film modified electrodes. / Ferancová, Adriana; Adamovski, Miriam; Gründler, Peter; Zima, Jiří; Barek, Jiří; Mattusch, Jürgen; Wennrich, Rainer; Labuda, Ján.

In: Bioelectrochemistry, Vol. 71, No. 1, 01.09.2007, p. 33-37.

Research output: Contribution to journalArticle

Ferancová, A, Adamovski, M, Gründler, P, Zima, J, Barek, J, Mattusch, J, Wennrich, R & Labuda, J 2007, 'Interaction of tin(II) and arsenic(III) with DNA at the nanostructure film modified electrodes', Bioelectrochemistry, vol. 71, no. 1, pp. 33-37. https://doi.org/10.1016/j.bioelechem.2006.07.013
Ferancová, Adriana ; Adamovski, Miriam ; Gründler, Peter ; Zima, Jiří ; Barek, Jiří ; Mattusch, Jürgen ; Wennrich, Rainer ; Labuda, Ján. / Interaction of tin(II) and arsenic(III) with DNA at the nanostructure film modified electrodes. In: Bioelectrochemistry. 2007 ; Vol. 71, No. 1. pp. 33-37.
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