Impairments to the Functions of Spatial Working Memory in Mild Depression and their Neurophysiological Correlates

S. A. Galkin, A. G. Peshkovskaya, G. G. Simutkin, S. N. Vasil’eva, O. V. Roshchina, S. A. Ivanova, N. A. Bokhan

Research output: Contribution to journalArticlepeer-review

Abstract

Objectives. To identify the characteristics of impairments to spatial working memory and their neurophysiological correlates in patients with mild depressive disorders. Materials and methods. A total of 30 patients (right-handed) with ICD-10 diagnoses of Mood Disorder (F31.3, F32.0, F33.0, F34.1) were studied before treatment started. Mean age was 37 ± 8 years. The control group consisted of 30 mentally and somatically healthy subjects (mean age 32 ± 7 years). Spatial working memory was investigated using the Corsi Block-Tapping test. Electroencephalography (EEG) studies were also run for analysis of spectral power in the θ, α, and β ranges. Results and conclusions. Decreases in spatial working memory were seen in mild depressive disorders and this corresponded to high EEG θ-rhythm power in the frontal and occipital areas and α-rhythm power in the frontal cortex.

Original languageEnglish
Pages (from-to)825-829
Number of pages5
JournalNeuroscience and Behavioral Physiology
Volume50
Issue number7
DOIs
Publication statusPublished - 1 Sep 2020
Externally publishedYes

Keywords

  • cognitive functions
  • depression
  • electroencephalographic correlates
  • spatial working memory

ASJC Scopus subject areas

  • Neuroscience(all)

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