Hypoiodite mediated synthesis of isoxazolines from aldoximes and alkenes using catalytic KI and Oxone as the terminal oxidant

Akira Yoshimura, Chenjie Zhu, Kyle R. Middleton, Anthony D. Todora, Brent J. Kastern, Andrey V. Maskaev, Viktor V. Zhdankin

Research output: Contribution to journalArticle

50 Citations (Scopus)

Abstract

Isoxazolines can be efficiently synthesized in good yields via a hypoiodite mediated catalytic oxidative cyclization of aldoximes and alkenes. This reaction involves active iodine species generated in situ from catalytic amounts of KI and Oxone.

Original languageEnglish
Pages (from-to)4800-4802
Number of pages3
JournalChemical Communications
Volume49
Issue number42
DOIs
Publication statusPublished - 25 May 2013
Externally publishedYes

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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