Abstract
An efficient synthetic procedure for di-cyano-cyclopropanation of alkenes using catalytic amounts of molecular iodine as a precatalyst and tert-butyl hydroperoxide (TBHP) as a terminal oxidant under mild conditions has been developed. This catalytic reaction works especially well for the aryl-substituted double bond affording products of cyclopropanation in high yields. A catalytic cycle based on the generated in situ hypoiodite species has been proposed,.
| Original language | English |
|---|---|
| Pages (from-to) | 3336-3340 |
| Number of pages | 5 |
| Journal | Advanced Synthesis and Catalysis |
| Volume | 356 |
| Issue number | 16 |
| DOIs | |
| Publication status | Published - 21 Sep 2014 |
Keywords
- Cyclopropanation
- Hypoiodite
- Iodine
- Organocatalysis
- Oxidation
ASJC Scopus subject areas
- Catalysis
- Organic Chemistry
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Yoshimura, A., Nicholas Jones, T., Yusubov, M. S., & Zhdankin, V. V. (2014). Hypoiodite-mediated catalytic cyclopropanation of alkenes with malononitrile. Advanced Synthesis and Catalysis, 356(16), 3336-3340. https://doi.org/10.1002/adsc.201400627