Abstract
An efficient synthetic procedure for di-cyano-cyclopropanation of alkenes using catalytic amounts of molecular iodine as a precatalyst and tert-butyl hydroperoxide (TBHP) as a terminal oxidant under mild conditions has been developed. This catalytic reaction works especially well for the aryl-substituted double bond affording products of cyclopropanation in high yields. A catalytic cycle based on the generated in situ hypoiodite species has been proposed,.
Original language | English |
---|---|
Pages (from-to) | 3336-3340 |
Number of pages | 5 |
Journal | Advanced Synthesis and Catalysis |
Volume | 356 |
Issue number | 16 |
DOIs | |
Publication status | Published - 21 Sep 2014 |
Keywords
- Cyclopropanation
- Hypoiodite
- Iodine
- Organocatalysis
- Oxidation
ASJC Scopus subject areas
- Catalysis
- Organic Chemistry