HPLC separation of genotoxic derivatives of naphthalene

V. Quaiserová, J. Zima, J. Barek

Research output: Contribution to journalArticlepeer-review


The following optimised conditions for the separation of naphthalene, naphthalen-1-amine, naphthalen-2-amine, 1-and 2-naphthols, and 1- and 2-nitronaphthalenes were found using a combination of the prediction of chromatographic behaviour of the tested substances with ChromSword® (Merck) optimisation software and experimental verification: LiChrospher® column, 24-min linear gradient, acetonitrile (40-70 %) -phosphate buffer, pH 2.3 (60-30 %), flow rate 0.5 ml.min-1, UV detection at 285 nm.

Original languageEnglish
Number of pages1
JournalChemicke Listy
Issue number11
Publication statusPublished - 1 Dec 2000
Externally publishedYes

ASJC Scopus subject areas

  • Chemistry(all)

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