HPLC monitoring of the efficiency of chemical decomposition of genotoxic fluoranthene derivatives

Jiri Zima, Alena Housova, Jiri Barek

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

A new RP HPLC method was developed for the separation and determination of fluoranthene, 3-aminofluoranthene and 3-nitrofluoranthene using a classical UV detector and a newly developed amperometric platinum tubular detector for 3-aminoliuoranthene. The detection limit of 3-aminofluoranthene was 1 × 10-7 mol L-1 with electrochemical detector and 3 × 10-7 mol L-1 with UV detector, and of fluoranthene and 3-nitrofluoranthene with UV detector was 1 × 10-7 mol L -1 and 3 × 10-7 mol L-1, respectively. The aim was to evaluate the efficiency of the chemical destruction of 3-nitrofluoranthene in laboratory wastes, as well as of the enzymatic oxidative destruction of 3-aminofluoranthene. 3-nitrofluoranthene was reduced with zinc, which preceded the oxidation with permanganate. In another approach the Fenton oxidizing reagent was used. The efficiency of the studied degradation methods for 3-aminofluoranthene and 3-nitrofluoranthene was at least 99%.

Original languageEnglish
Pages (from-to)509-519
Number of pages11
JournalChemia Analityczna
Volume48
Issue number3
Publication statusPublished - 27 Aug 2003
Externally publishedYes

Keywords

  • 3-aminofluoranthene
  • 3-nitrofluoranthene
  • Chemical destruction
  • Electrochemical detection
  • Fluoranthene
  • HPLC separation

ASJC Scopus subject areas

  • Analytical Chemistry

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