Abstract
In this work, the temperature dependence of Curie-spin (CS) contribution to the relaxation rate was studied by 1 H NMR under magnetic fields of 7.05 and 18.79 T using the Ho complex with DOTA as an example. This is the first example of the detailed study of the temperature dependence of Curie-spin contribution to the paramagnetic transverse relaxation rate enhancements (CS-PTRRE) in lanthanide complexes other than dysprosium, taking into account the magnetic field strength and change of viscosity with temperature. It was found that due to the substantial temperature dependence of CS-PTRRE the Ho complex with DOTA is the first example of a temperature sensitive relaxation paramagnetic lanthanide probe for in situ temperature control by NMR/MRI in water environment at high magnetic fields.
| Original language | English |
|---|---|
| Pages (from-to) | 57-60 |
| Number of pages | 4 |
| Journal | Inorganica Chimica Acta |
| Volume | 493 |
| DOIs | |
| Publication status | Published - 1 Jul 2019 |
| Externally published | Yes |
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Keywords
- Complexes of lanthanides
- DOTA
- Temperature sensitive NMR/MRI lanthanide paramagnetic relaxation probe
- The Curie-spin contribution to the paramagnetic relaxation rate enhancements
ASJC Scopus subject areas
- Physical and Theoretical Chemistry
- Inorganic Chemistry
- Materials Chemistry
Cite this
Holmium-DOTA as a responsive relaxation paramagnetic probe for NMR/MRI control of local temperature at high magnetic fields. / Babailov, Sergey P.; Zapolotsky, Eugeny N.; Basova, Tamara V.
In: Inorganica Chimica Acta, Vol. 493, 01.07.2019, p. 57-60.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Holmium-DOTA as a responsive relaxation paramagnetic probe for NMR/MRI control of local temperature at high magnetic fields
AU - Babailov, Sergey P.
AU - Zapolotsky, Eugeny N.
AU - Basova, Tamara V.
PY - 2019/7/1
Y1 - 2019/7/1
N2 - In this work, the temperature dependence of Curie-spin (CS) contribution to the relaxation rate was studied by 1 H NMR under magnetic fields of 7.05 and 18.79 T using the Ho complex with DOTA as an example. This is the first example of the detailed study of the temperature dependence of Curie-spin contribution to the paramagnetic transverse relaxation rate enhancements (CS-PTRRE) in lanthanide complexes other than dysprosium, taking into account the magnetic field strength and change of viscosity with temperature. It was found that due to the substantial temperature dependence of CS-PTRRE the Ho complex with DOTA is the first example of a temperature sensitive relaxation paramagnetic lanthanide probe for in situ temperature control by NMR/MRI in water environment at high magnetic fields.
AB - In this work, the temperature dependence of Curie-spin (CS) contribution to the relaxation rate was studied by 1 H NMR under magnetic fields of 7.05 and 18.79 T using the Ho complex with DOTA as an example. This is the first example of the detailed study of the temperature dependence of Curie-spin contribution to the paramagnetic transverse relaxation rate enhancements (CS-PTRRE) in lanthanide complexes other than dysprosium, taking into account the magnetic field strength and change of viscosity with temperature. It was found that due to the substantial temperature dependence of CS-PTRRE the Ho complex with DOTA is the first example of a temperature sensitive relaxation paramagnetic lanthanide probe for in situ temperature control by NMR/MRI in water environment at high magnetic fields.
KW - Complexes of lanthanides
KW - DOTA
KW - Temperature sensitive NMR/MRI lanthanide paramagnetic relaxation probe
KW - The Curie-spin contribution to the paramagnetic relaxation rate enhancements
UR - http://www.scopus.com/inward/record.url?scp=85065083520&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85065083520&partnerID=8YFLogxK
U2 - 10.1016/j.ica.2019.04.003
DO - 10.1016/j.ica.2019.04.003
M3 - Article
VL - 493
SP - 57
EP - 60
JO - Inorganica Chimica Acta
JF - Inorganica Chimica Acta
SN - 0020-1693
ER -