Histaminergic regulation of smooth muscles in rabbit pulmonary arteries

L. V. Kapilevich, Yana Jonovna Anfinogenova, A. V. Nosarev, M. B. Baskakov, I. V. Kovalev, E. Yu D'yakova, M. A. Medvedev

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Histaminergic contractile reactions of smooth muscles in rabbit lobar pulmonary arteries were studied using in vitro mechanographic technique. Histamine via activation of H-receptors induced a dose-dependent constriction of smooth muscle segments, while endothelium inhibited histamine-induced contractile reactions. Histamine increased sensitivity of smooth muscle cells in pulmonary artery to sodium nitroprusside.

Original languageEnglish
Pages (from-to)731-733
Number of pages3
JournalBulletin of Experimental Biology and Medicine
Volume132
Issue number2
DOIs
Publication statusPublished - 2001
Externally publishedYes

Keywords

  • Endothelium
  • Histamine
  • Pulmonary arteries
  • Smooth muscles

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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