TY - GEN
T1 - High physicochemical persistence of aluminum nanoparticles in synthetic body fluids
AU - Karepina, Elizaveta
AU - Godymchuk, Anna
AU - Kuznetsov, Denis
AU - Gusev, Alexander
PY - 2014
Y1 - 2014
N2 - When nanoparticles get into a living body, they interact with body fluids. This study shows high physicochemical persistence of electroexplosive aluminum nanoparticles in physiological solutions simulating body fluids: Artificial Sweat (ASw), Simulated Saliva (SS), Simulated Gastric Fluid (SGF), and Artificial Alveolar Fluid (AAF). It has been demonstrated that after 14 days of exposure in ASw - SS - SGF - AAF solutions, the average size of initial 90 nm nanoparticles became 90 - 100 - 230 - 90 nm, and the average size of initial 5 μm agglomerates became 1.6 - 0.9 - 1.0 - 3.0 μm, respectively. According to s SEM data, the exposed particles retained their spherical shape. With the help of the X-ray phase analysis it was shown that the oxide/hydroxide phase content in nanoparticles did not increase. It has been concluded that highlyreactive aluminum nanoparticles are capable to retain their phase composition, dispersion, and morphology in synthetic body fluids.
AB - When nanoparticles get into a living body, they interact with body fluids. This study shows high physicochemical persistence of electroexplosive aluminum nanoparticles in physiological solutions simulating body fluids: Artificial Sweat (ASw), Simulated Saliva (SS), Simulated Gastric Fluid (SGF), and Artificial Alveolar Fluid (AAF). It has been demonstrated that after 14 days of exposure in ASw - SS - SGF - AAF solutions, the average size of initial 90 nm nanoparticles became 90 - 100 - 230 - 90 nm, and the average size of initial 5 μm agglomerates became 1.6 - 0.9 - 1.0 - 3.0 μm, respectively. According to s SEM data, the exposed particles retained their spherical shape. With the help of the X-ray phase analysis it was shown that the oxide/hydroxide phase content in nanoparticles did not increase. It has been concluded that highlyreactive aluminum nanoparticles are capable to retain their phase composition, dispersion, and morphology in synthetic body fluids.
KW - Nanoparticles composition
KW - Nanoparticles dispersity
KW - Nanoparticles shape
KW - Synthetic body fluid
KW - Toxicity
UR - http://www.scopus.com/inward/record.url?scp=84891898521&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84891898521&partnerID=8YFLogxK
U2 - 10.4028/www.scientific.net/AMR.872.248
DO - 10.4028/www.scientific.net/AMR.872.248
M3 - Conference contribution
AN - SCOPUS:84891898521
SN - 9783037859667
VL - 872
T3 - Advanced Materials Research
SP - 248
EP - 256
BT - Advanced Materials Research
T2 - Russian-German Forum on Nanotechnology
Y2 - 21 May 2013 through 24 May 2013
ER -