Heterocyclization of o-(arylethynyl)arylhydrazines as a new procedure for the synthesis of substituted 1H-and 2H-indazoles and indoles

T. A. Prikhodko, S. F. Vasilevsky

Research output: Contribution to journalArticle

11 Citations (Scopus)


Procedures for the preparation of 3-substituted 1H-and 2H-indazoles and 2-substituted indoles were developed based on cross-coupling of o-iodoarylhydrazines with copper acetylenides in pyridine or dimethylformamide. An alternative procedure for the synthesis of 3-substituted 1H-indazoles involves cyclocondensation of (2-chloroaryl)acetylenes with hydrazine hydrate in butanol.

Original languageEnglish
Pages (from-to)1268-1273
Number of pages6
JournalRussian Chemical Bulletin
Issue number7
Publication statusPublished - 1 Dec 2001
Externally publishedYes



  • Cross-coupling
  • Heterocyclization
  • Indazoles
  • Indoles
  • Isoindazoles
  • O-chloroarylacetylenes
  • O-iodoarylhydrazines

ASJC Scopus subject areas

  • Chemistry(all)

Cite this