Abstract
A good exchange: 5-Iodo-1,2,3-triazoles undergo facile substitution reactions with fluoride salts, thus providing ready access to 5-fluorotriazoles (see scheme). The latter can be further elaborated with various nucleophiles to furnish fully substituted 1,2,3-triazole compounds.
Original language | English |
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Pages (from-to) | 11791-11794 |
Number of pages | 4 |
Journal | Angewandte Chemie - International Edition |
Volume | 51 |
Issue number | 47 |
DOIs | |
Publication status | Published - 19 Nov 2012 |
Externally published | Yes |
Keywords
- click chemistry
- fluorine
- heterocycles
- imaging agents
- nucleophilic substitution
ASJC Scopus subject areas
- Chemistry(all)
- Catalysis