Fabrication and characterization of polycaprolactone cross- linked and highly-aligned 3-D artificial scaffolds for bone tissue regeneration via electrospinning technology

Research output: Chapter in Book/Report/Conference proceedingConference contribution

6 Citations (Scopus)

Abstract

Novel technologies allowed the scientific community to develop scaffolds for regeneration of bone tissue. A successful scaffold should possess specific macroscopic geometry and internal architecture to perform biological and biophysical functions. In this study the process of polycaprolactone microfibrous development with either cross-linked or highly-aligned three-dimensional artificial mats via electrospinning technology for potential application in tissue engineering is described. The morphology and size of electrospun fibers were assessed systematically by varying the rotation speed of grounded collector. It was found that the diameter of the fibers decreased by increasing the rotation speed of collector. The morphology of the fibers changed from cross-linked to highly-aligned at appr. 1000-1100 rpm.

Original languageEnglish
Title of host publicationIOP Conference Series: Materials Science and Engineering
PublisherInstitute of Physics Publishing
Volume98
Edition1
DOIs
Publication statusPublished - 3 Nov 2015
Event3rd International Youth Conference on Interdisciplinary Problems of Nanotechnology, Biomedicine and Nanotoxicology, Nanobiotech 2015 - Tambov, Russian Federation
Duration: 21 May 201522 May 2015

Other

Other3rd International Youth Conference on Interdisciplinary Problems of Nanotechnology, Biomedicine and Nanotoxicology, Nanobiotech 2015
CountryRussian Federation
CityTambov
Period21.5.1522.5.15

Fingerprint

Tissue regeneration
Polycaprolactone
Electrospinning
Scaffolds
Bone
Fabrication
Fibers
Bioelectric potentials
Tissue engineering
Tissue
Geometry
polycaprolactone

ASJC Scopus subject areas

  • Engineering(all)
  • Materials Science(all)

Cite this

Fabrication and characterization of polycaprolactone cross- linked and highly-aligned 3-D artificial scaffolds for bone tissue regeneration via electrospinning technology. / Gorodzha, Svetlana Nikolaevna; Surmeneva, M. A.; Surmenev, R. A.

IOP Conference Series: Materials Science and Engineering. Vol. 98 1. ed. Institute of Physics Publishing, 2015. 012024.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Gorodzha, SN, Surmeneva, MA & Surmenev, RA 2015, Fabrication and characterization of polycaprolactone cross- linked and highly-aligned 3-D artificial scaffolds for bone tissue regeneration via electrospinning technology. in IOP Conference Series: Materials Science and Engineering. 1 edn, vol. 98, 012024, Institute of Physics Publishing, 3rd International Youth Conference on Interdisciplinary Problems of Nanotechnology, Biomedicine and Nanotoxicology, Nanobiotech 2015, Tambov, Russian Federation, 21.5.15. https://doi.org/10.1088/1757-899X/98/1/012024
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