Abstract
A simple and convenient synthesis of ω-iodoaliphatic carboxylic acids and esters by the reaction of cyclic ketones with iodine and hydrogen peroxide in the presence of catalytic CuCl has been developed. ω-Iodoaliphatic carboxylic esters were further used for the efficient preparation of di(2-pyridylmethylamino)alkanoic acids in excellent yields.
Original language | English |
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Pages (from-to) | 4081-4088 |
Number of pages | 8 |
Journal | Synthesis (Germany) |
Volume | 50 |
Issue number | 20 |
DOIs | |
Publication status | Published - 1 Jan 2018 |
Keywords
- chelating reagents
- cyclic ketones
- di-(2-picolyl)amine
- di-(2-pyridylmethylamino)alkanoic acids
- ligands
- ω-iodo-aliphatic carboxylic esters
- ω-iodoaliphatic carboxylic acids
ASJC Scopus subject areas
- Catalysis
- Organic Chemistry