Evaluation of Ag containing hydroxyapatite coatings to the Candida albicans infection

Abstract

In this research work, the synthesis of Ag doped hydroxyapatite coatings for dental or orthopedic implants was performed. The main goal was to determine the influence of Ag content on the roughness and antimicrobial performance of the prepared thin films. The films were deposited on Ti6Al4V alloy by means of RF magnetron sputtering. Those coatings were characterized by X-ray diffraction (XRD) and 3D surface profilometry. The antifungal activity after 1 and 7 days of culture was evaluated in the presence of Candida albicans (ATCC - 10231). The increase of Ag content increased roughness and reduced the antifungal activity. The results showed that the Ag doped hydroxyapatite coatings can be a potential solution for the improvement of the antifungal activities of Ti based alloy.

Original language	English
Pages (from-to)	12-18
Number of pages	7
Journal	Journal of Microbiological Methods
Volume	125
DOIs	https://doi.org/10.1016/j.mimet.2016.03.016
Publication status	Published - 1 Jun 2016
Externally published	Yes

Keywords

Biomedical applications
Magnetron sputtering
Roughness
Silver

ASJC Scopus subject areas

Microbiology
Molecular Biology
Microbiology (medical)

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10.1016/j.mimet.2016.03.016

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title = "Evaluation of Ag containing hydroxyapatite coatings to the Candida albicans infection",

abstract = "In this research work, the synthesis of Ag doped hydroxyapatite coatings for dental or orthopedic implants was performed. The main goal was to determine the influence of Ag content on the roughness and antimicrobial performance of the prepared thin films. The films were deposited on Ti6Al4V alloy by means of RF magnetron sputtering. Those coatings were characterized by X-ray diffraction (XRD) and 3D surface profilometry. The antifungal activity after 1 and 7 days of culture was evaluated in the presence of Candida albicans (ATCC - 10231). The increase of Ag content increased roughness and reduced the antifungal activity. The results showed that the Ag doped hydroxyapatite coatings can be a potential solution for the improvement of the antifungal activities of Ti based alloy.",

keywords = "Biomedical applications, Magnetron sputtering, Roughness, Silver",

author = "S. Ciuca and M. Badea and E. Pozna and I. Pana and A. Kiss and L. Floroian and A. Semenescu and Cotrut, {C. M.} and M. Moga and A. Vladescu",

year = "2016",

month = jun,

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doi = "10.1016/j.mimet.2016.03.016",

language = "English",

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pages = "12--18",

journal = "Journal of Microbiological Methods",

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TY - JOUR

T1 - Evaluation of Ag containing hydroxyapatite coatings to the Candida albicans infection

AU - Ciuca, S.

AU - Badea, M.

AU - Pozna, E.

AU - Pana, I.

AU - Kiss, A.

AU - Floroian, L.

AU - Semenescu, A.

AU - Cotrut, C. M.

AU - Moga, M.

AU - Vladescu, A.

PY - 2016/6/1

Y1 - 2016/6/1

N2 - In this research work, the synthesis of Ag doped hydroxyapatite coatings for dental or orthopedic implants was performed. The main goal was to determine the influence of Ag content on the roughness and antimicrobial performance of the prepared thin films. The films were deposited on Ti6Al4V alloy by means of RF magnetron sputtering. Those coatings were characterized by X-ray diffraction (XRD) and 3D surface profilometry. The antifungal activity after 1 and 7 days of culture was evaluated in the presence of Candida albicans (ATCC - 10231). The increase of Ag content increased roughness and reduced the antifungal activity. The results showed that the Ag doped hydroxyapatite coatings can be a potential solution for the improvement of the antifungal activities of Ti based alloy.

AB - In this research work, the synthesis of Ag doped hydroxyapatite coatings for dental or orthopedic implants was performed. The main goal was to determine the influence of Ag content on the roughness and antimicrobial performance of the prepared thin films. The films were deposited on Ti6Al4V alloy by means of RF magnetron sputtering. Those coatings were characterized by X-ray diffraction (XRD) and 3D surface profilometry. The antifungal activity after 1 and 7 days of culture was evaluated in the presence of Candida albicans (ATCC - 10231). The increase of Ag content increased roughness and reduced the antifungal activity. The results showed that the Ag doped hydroxyapatite coatings can be a potential solution for the improvement of the antifungal activities of Ti based alloy.

KW - Biomedical applications

KW - Magnetron sputtering

KW - Roughness

KW - Silver

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