TY - JOUR
T1 - Evaluation of Ag containing hydroxyapatite coatings to the Candida albicans infection
AU - Ciuca, S.
AU - Badea, M.
AU - Pozna, E.
AU - Pana, I.
AU - Kiss, A.
AU - Floroian, L.
AU - Semenescu, A.
AU - Cotrut, C. M.
AU - Moga, M.
AU - Vladescu, A.
PY - 2016/6/1
Y1 - 2016/6/1
N2 - In this research work, the synthesis of Ag doped hydroxyapatite coatings for dental or orthopedic implants was performed. The main goal was to determine the influence of Ag content on the roughness and antimicrobial performance of the prepared thin films. The films were deposited on Ti6Al4V alloy by means of RF magnetron sputtering. Those coatings were characterized by X-ray diffraction (XRD) and 3D surface profilometry. The antifungal activity after 1 and 7 days of culture was evaluated in the presence of Candida albicans (ATCC - 10231). The increase of Ag content increased roughness and reduced the antifungal activity. The results showed that the Ag doped hydroxyapatite coatings can be a potential solution for the improvement of the antifungal activities of Ti based alloy.
AB - In this research work, the synthesis of Ag doped hydroxyapatite coatings for dental or orthopedic implants was performed. The main goal was to determine the influence of Ag content on the roughness and antimicrobial performance of the prepared thin films. The films were deposited on Ti6Al4V alloy by means of RF magnetron sputtering. Those coatings were characterized by X-ray diffraction (XRD) and 3D surface profilometry. The antifungal activity after 1 and 7 days of culture was evaluated in the presence of Candida albicans (ATCC - 10231). The increase of Ag content increased roughness and reduced the antifungal activity. The results showed that the Ag doped hydroxyapatite coatings can be a potential solution for the improvement of the antifungal activities of Ti based alloy.
KW - Biomedical applications
KW - Magnetron sputtering
KW - Roughness
KW - Silver
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U2 - 10.1016/j.mimet.2016.03.016
DO - 10.1016/j.mimet.2016.03.016
M3 - Article
C2 - 27021660
AN - SCOPUS:84962425337
VL - 125
SP - 12
EP - 18
JO - Journal of Microbiological Methods
JF - Journal of Microbiological Methods
SN - 0167-7012
ER -