Evaluation of Ag containing hydroxyapatite coatings to the Candida albicans infection

S. Ciuca, M. Badea, E. Pozna, I. Pana, A. Kiss, L. Floroian, A. Semenescu, C. M. Cotrut, M. Moga, A. Vladescu

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)

Abstract

In this research work, the synthesis of Ag doped hydroxyapatite coatings for dental or orthopedic implants was performed. The main goal was to determine the influence of Ag content on the roughness and antimicrobial performance of the prepared thin films. The films were deposited on Ti6Al4V alloy by means of RF magnetron sputtering. Those coatings were characterized by X-ray diffraction (XRD) and 3D surface profilometry. The antifungal activity after 1 and 7 days of culture was evaluated in the presence of Candida albicans (ATCC - 10231). The increase of Ag content increased roughness and reduced the antifungal activity. The results showed that the Ag doped hydroxyapatite coatings can be a potential solution for the improvement of the antifungal activities of Ti based alloy.

Original languageEnglish
Pages (from-to)12-18
Number of pages7
JournalJournal of Microbiological Methods
Volume125
DOIs
Publication statusPublished - 1 Jun 2016
Externally publishedYes

Keywords

  • Biomedical applications
  • Magnetron sputtering
  • Roughness
  • Silver

ASJC Scopus subject areas

  • Microbiology
  • Molecular Biology
  • Microbiology (medical)

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