Ethyl vinyl ether - An agent for protection of the pyrazole NH-fragment. A convenient method for the preparation of N-unsubstituted 4-alkynylpyrazoles

Sergei F. Vasilevsky, Svetlana V. Klyatskaya, Eugene V. Tretyakov, José Elguero

Research output: Contribution to journalArticlepeer-review

17 Citations (Scopus)

Abstract

N-Unsubstituted 4-iodopyrazole (1) is easily converted into 4-alkynyl derivatives (5) in moderate to good overall yields by using intermediate protection of the nitrogen atom of the pyrazole ring by ethyl vinyl ether.

Original languageEnglish
Pages (from-to)879-886
Number of pages8
JournalHeterocycles
Volume60
Issue number4
Publication statusPublished - 1 Apr 2003
Externally publishedYes

ASJC Scopus subject areas

  • Analytical Chemistry
  • Pharmacology
  • Organic Chemistry

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