Abstract
In this paper the possibility of estimation of the parameters of the blood clotting process using the photometry study of droplet samples is shown. The theoretical justification and results of experimental research using proposed method, the example of determination of prothrombin time are presented. Experimental data were used to analyse shapes of the curves obtained at the studying. Dependence of the curve shape on the location of the radiation detector was also analysed. It was determined that the most informative curves are obtained when the receiver location is in the optical focus of the sample droplet. The possibility of monitoring of the dynamics of the process is demonstrated. The paper presents the advantages of droplet samples using for study of the coagulation process. Proposed method allows to reduce the amount of reagents, to increase sensitivity of the analysis and eliminate the subjective factor.
| Original language | English |
|---|---|
| Title of host publication | Proceedings of 2014 International Conference on Mechanical Engineering, Automation and Control Systems, MEACS 2014 |
| Publisher | Institute of Electrical and Electronics Engineers Inc. |
| ISBN (Print) | 9781479962211 |
| DOIs | |
| Publication status | Published - 15 Dec 2014 |
| Event | 2014 International Conference on Mechanical Engineering, Automation and Control Systems, MEACS 2014 - Tomsk, Russian Federation Duration: 16 Oct 2014 → 18 Oct 2014 |
Other
| Other | 2014 International Conference on Mechanical Engineering, Automation and Control Systems, MEACS 2014 |
|---|---|
| Country | Russian Federation |
| City | Tomsk |
| Period | 16.10.14 → 18.10.14 |
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Keywords
- blood coagulation
- drop
- fibrin clot
- optical system
- plasma
ASJC Scopus subject areas
- Mechanical Engineering
- Electrical and Electronic Engineering
- Control and Systems Engineering
Cite this
Estimation of blood clotting in the drip samples using optical methods. / Aristov, Alexander Alexandrovich; Zhoglo, E. V.
Proceedings of 2014 International Conference on Mechanical Engineering, Automation and Control Systems, MEACS 2014. Institute of Electrical and Electronics Engineers Inc., 2014. 6986910.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - Estimation of blood clotting in the drip samples using optical methods
AU - Aristov, Alexander Alexandrovich
AU - Zhoglo, E. V.
PY - 2014/12/15
Y1 - 2014/12/15
N2 - In this paper the possibility of estimation of the parameters of the blood clotting process using the photometry study of droplet samples is shown. The theoretical justification and results of experimental research using proposed method, the example of determination of prothrombin time are presented. Experimental data were used to analyse shapes of the curves obtained at the studying. Dependence of the curve shape on the location of the radiation detector was also analysed. It was determined that the most informative curves are obtained when the receiver location is in the optical focus of the sample droplet. The possibility of monitoring of the dynamics of the process is demonstrated. The paper presents the advantages of droplet samples using for study of the coagulation process. Proposed method allows to reduce the amount of reagents, to increase sensitivity of the analysis and eliminate the subjective factor.
AB - In this paper the possibility of estimation of the parameters of the blood clotting process using the photometry study of droplet samples is shown. The theoretical justification and results of experimental research using proposed method, the example of determination of prothrombin time are presented. Experimental data were used to analyse shapes of the curves obtained at the studying. Dependence of the curve shape on the location of the radiation detector was also analysed. It was determined that the most informative curves are obtained when the receiver location is in the optical focus of the sample droplet. The possibility of monitoring of the dynamics of the process is demonstrated. The paper presents the advantages of droplet samples using for study of the coagulation process. Proposed method allows to reduce the amount of reagents, to increase sensitivity of the analysis and eliminate the subjective factor.
KW - blood coagulation
KW - drop
KW - fibrin clot
KW - optical system
KW - plasma
UR - http://www.scopus.com/inward/record.url?scp=84922573102&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84922573102&partnerID=8YFLogxK
U2 - 10.1109/MEACS.2014.6986910
DO - 10.1109/MEACS.2014.6986910
M3 - Conference contribution
SN - 9781479962211
BT - Proceedings of 2014 International Conference on Mechanical Engineering, Automation and Control Systems, MEACS 2014
PB - Institute of Electrical and Electronics Engineers Inc.
ER -