Estimation of blood clotting in the drip samples using optical methods

Abstract

In this paper the possibility of estimation of the parameters of the blood clotting process using the photometry study of droplet samples is shown. The theoretical justification and results of experimental research using proposed method, the example of determination of prothrombin time are presented. Experimental data were used to analyse shapes of the curves obtained at the studying. Dependence of the curve shape on the location of the radiation detector was also analysed. It was determined that the most informative curves are obtained when the receiver location is in the optical focus of the sample droplet. The possibility of monitoring of the dynamics of the process is demonstrated. The paper presents the advantages of droplet samples using for study of the coagulation process. Proposed method allows to reduce the amount of reagents, to increase sensitivity of the analysis and eliminate the subjective factor.

Original language	English
Title of host publication	Proceedings of 2014 International Conference on Mechanical Engineering, Automation and Control Systems, MEACS 2014
Publisher	Institute of Electrical and Electronics Engineers Inc.
ISBN (Print)	9781479962211
DOIs	https://doi.org/10.1109/MEACS.2014.6986910
Publication status	Published - 15 Dec 2014
Event	2014 International Conference on Mechanical Engineering, Automation and Control Systems, MEACS 2014 - Tomsk, Russian Federation Duration: 16 Oct 2014 → 18 Oct 2014

Other

Other	2014 International Conference on Mechanical Engineering, Automation and Control Systems, MEACS 2014
Country	Russian Federation
City	Tomsk
Period	16.10.14 → 18.10.14

Keywords

blood coagulation
drop
fibrin clot
optical system
plasma

ASJC Scopus subject areas

Mechanical Engineering
Electrical and Electronic Engineering
Control and Systems Engineering

Access to Document

10.1109/MEACS.2014.6986910

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Estimation of blood clotting in the drip samples using optical methods. / Aristov, Alexander Alexandrovich; Zhoglo, E. V.

Proceedings of 2014 International Conference on Mechanical Engineering, Automation and Control Systems, MEACS 2014. Institute of Electrical and Electronics Engineers Inc., 2014. 6986910.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Aristov, AA & Zhoglo, EV 2014, Estimation of blood clotting in the drip samples using optical methods. in Proceedings of 2014 International Conference on Mechanical Engineering, Automation and Control Systems, MEACS 2014., 6986910, Institute of Electrical and Electronics Engineers Inc., 2014 International Conference on Mechanical Engineering, Automation and Control Systems, MEACS 2014, Tomsk, Russian Federation, 16.10.14. https://doi.org/10.1109/MEACS.2014.6986910

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