Abstract
The electrochemical behavior of a number of benzoyl barbiturates was studied using a glassy carbon electrode (GCE). The kinetics of the electrode process is determined, the contribution of physical adsorption to the electrochemical process is estimated, and the mechanism of the possible electrochemical reaction is proposed. It is shown that the electrochemical reduction potentials of benzoyl phenobarbital derivatives are determined by the LUMO energies, calculated by the B3LYP 6-311+G method. It is established that the process is quasi-reversible, complicated by adverse reactions. The influence of halogen type and its position in the benzoyl residue of the studied substances on the analytical signal is established. The effective values of the dissociation constants of various forms of benzoyl derivatives were calculated using the example of halonal, for which the values 3.16 ⋅ 10−8 and 6.31 ⋅ 10−12, respectively, were found.
| Original language | English |
|---|---|
| Pages (from-to) | 1494-1500 |
| Number of pages | 7 |
| Journal | Electroanalysis |
| Volume | 31 |
| Issue number | 8 |
| DOIs | |
| Publication status | Published - 1 Jan 2019 |
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Keywords
- Benzoyl derivatives of barbituric acid
- differential pulse voltammetry
- glassy carbon electrode
- mechanism of electrochemical reaction
ASJC Scopus subject areas
- Analytical Chemistry
- Electrochemistry
Cite this
Electrochemical Characterization and Voltammetric Determination of Benzoyl Derivatives of Phenobarbital Using Glassy Carbon Electrode. / Mezentseva, Olga; Slepchenko, Galina; Filimonov, Victor; Mikheeva, Elena; Arbit, Galina.
In: Electroanalysis, Vol. 31, No. 8, 01.01.2019, p. 1494-1500.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Electrochemical Characterization and Voltammetric Determination of Benzoyl Derivatives of Phenobarbital Using Glassy Carbon Electrode
AU - Mezentseva, Olga
AU - Slepchenko, Galina
AU - Filimonov, Victor
AU - Mikheeva, Elena
AU - Arbit, Galina
PY - 2019/1/1
Y1 - 2019/1/1
N2 - The electrochemical behavior of a number of benzoyl barbiturates was studied using a glassy carbon electrode (GCE). The kinetics of the electrode process is determined, the contribution of physical adsorption to the electrochemical process is estimated, and the mechanism of the possible electrochemical reaction is proposed. It is shown that the electrochemical reduction potentials of benzoyl phenobarbital derivatives are determined by the LUMO energies, calculated by the B3LYP 6-311+G method. It is established that the process is quasi-reversible, complicated by adverse reactions. The influence of halogen type and its position in the benzoyl residue of the studied substances on the analytical signal is established. The effective values of the dissociation constants of various forms of benzoyl derivatives were calculated using the example of halonal, for which the values 3.16 ⋅ 10−8 and 6.31 ⋅ 10−12, respectively, were found.
AB - The electrochemical behavior of a number of benzoyl barbiturates was studied using a glassy carbon electrode (GCE). The kinetics of the electrode process is determined, the contribution of physical adsorption to the electrochemical process is estimated, and the mechanism of the possible electrochemical reaction is proposed. It is shown that the electrochemical reduction potentials of benzoyl phenobarbital derivatives are determined by the LUMO energies, calculated by the B3LYP 6-311+G method. It is established that the process is quasi-reversible, complicated by adverse reactions. The influence of halogen type and its position in the benzoyl residue of the studied substances on the analytical signal is established. The effective values of the dissociation constants of various forms of benzoyl derivatives were calculated using the example of halonal, for which the values 3.16 ⋅ 10−8 and 6.31 ⋅ 10−12, respectively, were found.
KW - Benzoyl derivatives of barbituric acid
KW - differential pulse voltammetry
KW - glassy carbon electrode
KW - mechanism of electrochemical reaction
UR - http://www.scopus.com/inward/record.url?scp=85066883882&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85066883882&partnerID=8YFLogxK
U2 - 10.1002/elan.201900179
DO - 10.1002/elan.201900179
M3 - Article
VL - 31
SP - 1494
EP - 1500
JO - Macromolecular Chemistry and Physics
JF - Macromolecular Chemistry and Physics
SN - 1040-0397
IS - 8
ER -