Efficient synthesis of 1-sulfonyl-1,2,3-triazoles

Jessica Raushel, Valery V. Fokin

Research output: Contribution to journalArticle

175 Citations (Scopus)

Abstract

An efficient room-temperature method for the synthesis of 1-sulfonyl-1,2,3-triazoles from in situ generated copper(I) acetylides and sulfonyl azides is described. The copper(I) thiophene-2-carboxylate (CuTC) catalyst produces the title compounds under both nonbasic anhydrous and aqueous conditions in good yields.

Original languageEnglish
Pages (from-to)4952-4955
Number of pages4
JournalOrganic Letters
Volume12
Issue number21
DOIs
Publication statusPublished - 5 Nov 2010
Externally publishedYes

Fingerprint

Copper
copper
Azides
synthesis
thiophenes
carboxylates
catalysts
Catalysts
Temperature
room temperature
1-sulfonyl-1,2,3-triazole
thiophene-2-carboxylate

ASJC Scopus subject areas

  • Organic Chemistry
  • Physical and Theoretical Chemistry
  • Biochemistry

Cite this

Efficient synthesis of 1-sulfonyl-1,2,3-triazoles. / Raushel, Jessica; Fokin, Valery V.

In: Organic Letters, Vol. 12, No. 21, 05.11.2010, p. 4952-4955.

Research output: Contribution to journalArticle

Raushel, J & Fokin, VV 2010, 'Efficient synthesis of 1-sulfonyl-1,2,3-triazoles', Organic Letters, vol. 12, no. 21, pp. 4952-4955. https://doi.org/10.1021/ol102087r
Raushel, Jessica ; Fokin, Valery V. / Efficient synthesis of 1-sulfonyl-1,2,3-triazoles. In: Organic Letters. 2010 ; Vol. 12, No. 21. pp. 4952-4955.
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