Efficacy of silver nanoparticles against the adults and eggs of monogenean parasites of fish

Citlalic Altagracia Pimentel-Acosta, Francisco Neptalí Morales-Serna, María Cristina Chávez-Sánchez, Humberto Herman Lara, Alexey Pestryakov, Nina Bogdanchikova, Emma Josefina Fajer-Ávila

Research output: Contribution to journalArticle

Abstract

Monogeneans are a diverse group of parasites that are commonly found on fish. Some monogenean species are highly pathogenic to cultured fish. The present study aimed to determine the in vitro anthelmintic effect of silver nanoparticles (AgNPs) against adults and eggs of monogeneans in freshwater using Cichlidogyrus spp. as a model organism. We tested two types of AgNPs with different synthesis methodologies and size diameters: ARGOVIT (35 nm) and UTSA (1–3 nm) nanoparticles. Damage to the parasite tegument was observed by scanning electron microscopy. UTSA AgNPs were more effective than ARGOVIT; in both cases, there was a concentration-dependent effect. A concentration of 36 μg/L UTSA AgNPs for 1 h was 100% effective against eggs and adult parasites, causing swelling, loss of corrugations, and disruption of the parasite’s tegument. This is an interesting result considering that monogenean eggs are typically tolerant to antiparasite drugs and chemical agents. To the best of our knowledge, no previous reports have assessed the effect of AgNPs on any metazoan parasites of fish. Therefore, the present work provides a basis for future research on the control of fish parasite diseases.

Original languageEnglish
Pages (from-to)1741-1749
Number of pages9
JournalParasitology Research
Volume118
Issue number6
DOIs
Publication statusPublished - 1 Jun 2019

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Keywords

  • Control disease
  • Platyhelminthes
  • Silver nanoparticles
  • Tegument
  • Toxicity

ASJC Scopus subject areas

  • Parasitology
  • veterinary(all)
  • Insect Science
  • Infectious Diseases

Cite this

Pimentel-Acosta, C. A., Morales-Serna, F. N., Chávez-Sánchez, M. C., Lara, H. H., Pestryakov, A., Bogdanchikova, N., & Fajer-Ávila, E. J. (2019). Efficacy of silver nanoparticles against the adults and eggs of monogenean parasites of fish. Parasitology Research, 118(6), 1741-1749. https://doi.org/10.1007/s00436-019-06315-9