Effects of Humic Acids, Isolated from High-Moor Pine-Peat Moss-Cotton Grass Peat on the Production of Cytokines by Mouse and Human Immunocompetent Cells and on Humoral Immune Response

E. S. Trofimova, M. V. Zykova, E. Yu Sherstoboev, M. G. Danilets, A. A. Ligacheva, M. V. Belousov

Research output: Contribution to journalArticle

Abstract

A course of treatment with humic acids extracted with sodium pyrophosphate from high-moor pine-peat moss-cotton grass peat improves humoral immune response of C57BL/6 mice, stimulates the production of TNFα, IL-1β, and IL-12 by the animal peritoneal macrophages and the production of IFNγ and TNFα by donor peripheral blood mononuclears, causing no changes in the production of IL-10 in vitro.

Original languageEnglish
Pages (from-to)651-653
Number of pages3
JournalBulletin of Experimental Biology and Medicine
Volume168
Issue number5
DOIs
Publication statusPublished - 1 Mar 2020

Keywords

  • cytokines
  • humic acids
  • humoral immune response

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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