Effect of nitro derivatives on electromechanical coupling in ureteral smooth muscle cells

Abstract

Double sucrose gap experiments revealed differences in the effect of nitroglycerin and sodium nitroprusside on action potential and contraction of ureteral smooth muscle cells. Unlike sodium nitroprusside, nitroglycerin inhibited voltage-dependent Ca²⁺ membrane permeability. It was concluded that cGMP-independent mechanisms of the effects of nitro derivative reflect the peculiarities of excitation-contraction coupling in smooth muscles.

Original language	English
Pages (from-to)	455-457
Number of pages	3
Journal	Bulletin of Experimental Biology and Medicine
Volume	129
Issue number	5
Publication status	Published - 2000
Externally published	Yes

Keywords

Ionic membrane permeability
Nitro derivatives
Smooth muscle cells

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)

Fingerprint Dive into the research topics of 'Effect of nitro derivatives on electromechanical coupling in ureteral smooth muscle cells'. Together they form a unique fingerprint.

Cite this

Effect of nitro derivatives on electromechanical coupling in ureteral smooth muscle cells. / Kovalev, I. V.; Popov, A. G.; Panov, A. A.; Borodin, Yu L.; Kapilevich, L. V.; Anfinogenova, Yana Jonovna; Baskakov, M. B.; Medvedev, M. A.

In: Bulletin of Experimental Biology and Medicine, Vol. 129, No. 5, 2000, p. 455-457.

Research output: Contribution to journal › Article › peer-review

@article{8be900a777e24affa18e15ef2181e88c,

title = "Effect of nitro derivatives on electromechanical coupling in ureteral smooth muscle cells",

abstract = "Double sucrose gap experiments revealed differences in the effect of nitroglycerin and sodium nitroprusside on action potential and contraction of ureteral smooth muscle cells. Unlike sodium nitroprusside, nitroglycerin inhibited voltage-dependent Ca2+ membrane permeability. It was concluded that cGMP-independent mechanisms of the effects of nitro derivative reflect the peculiarities of excitation-contraction coupling in smooth muscles.",

keywords = "Ionic membrane permeability, Nitro derivatives, Smooth muscle cells",

author = "Kovalev, {I. V.} and Popov, {A. G.} and Panov, {A. A.} and Borodin, {Yu L.} and Kapilevich, {L. V.} and Anfinogenova, {Yana Jonovna} and Baskakov, {M. B.} and Medvedev, {M. A.}",

year = "2000",

language = "English",

volume = "129",

pages = "455--457",

journal = "Bulletin of Experimental Biology and Medicine",

issn = "0007-4888",

publisher = "Springer New York",

number = "5",

}

TY - JOUR

T1 - Effect of nitro derivatives on electromechanical coupling in ureteral smooth muscle cells

AU - Kovalev, I. V.

AU - Popov, A. G.

AU - Panov, A. A.

AU - Borodin, Yu L.

AU - Kapilevich, L. V.

AU - Anfinogenova, Yana Jonovna

AU - Baskakov, M. B.

AU - Medvedev, M. A.

PY - 2000

Y1 - 2000

N2 - Double sucrose gap experiments revealed differences in the effect of nitroglycerin and sodium nitroprusside on action potential and contraction of ureteral smooth muscle cells. Unlike sodium nitroprusside, nitroglycerin inhibited voltage-dependent Ca2+ membrane permeability. It was concluded that cGMP-independent mechanisms of the effects of nitro derivative reflect the peculiarities of excitation-contraction coupling in smooth muscles.

AB - Double sucrose gap experiments revealed differences in the effect of nitroglycerin and sodium nitroprusside on action potential and contraction of ureteral smooth muscle cells. Unlike sodium nitroprusside, nitroglycerin inhibited voltage-dependent Ca2+ membrane permeability. It was concluded that cGMP-independent mechanisms of the effects of nitro derivative reflect the peculiarities of excitation-contraction coupling in smooth muscles.

KW - Ionic membrane permeability

KW - Nitro derivatives

KW - Smooth muscle cells

UR - http://www.scopus.com/inward/record.url?scp=0033786497&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0033786497&partnerID=8YFLogxK

M3 - Article

C2 - 10977949

AN - SCOPUS:0033786497

VL - 129

SP - 455

EP - 457

JO - Bulletin of Experimental Biology and Medicine

JF - Bulletin of Experimental Biology and Medicine

SN - 0007-4888

IS - 5

ER -