Lithium hydroxybutyrate (10 mg/kg daily for 10 days, intramuscularly) administered in the morning prevents reserpine-induced depression of the diurnal steroidogenesis in mice and the development of desynchronosis between circadian rhythms of serotonin in the brain and plasma corticosteroids. Evening injections result in the formation of phase-discordant 24-h periodicities, the mean values of the studied parameters being unaffected.
|Number of pages||4|
|Journal||Bulletin of Experimental Biology and Medicine|
|Publication status||Published - 1 Jul 1997|
- Circadian rhythms
- Lithium hydroxybutyrate
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)