Effect of ligands of opiate receptors on morphofunctional state of the sympathoadrenal system and electrical stability of the heart in acute cold exposure

Yu B. Lishmanov, B. Yu Kondrat'ev, L. N. Maslov, N. V. Naryzhnaya

Research output: Contribution to journalArticle

Abstract

Acute cold exposure (-20°C, 4 h) induces a transient decrease in the ventricular fibrillation threshold without morphological and radionuclide signs of irreversible damage to cardiomyocytes. The agonist of μ-receptors DAGO, which reduces adrenoreactivity of the myocardium, prevents the decrease in the ventricular fibrillation threshold induced by acute cold exposure.

Original languageEnglish
Pages (from-to)130-132
Number of pages3
JournalBulletin of Experimental Biology and Medicine
Volume123
Issue number2
Publication statusPublished - Feb 1997

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Ala(2)-MePhe(4)-Gly(5)-enkephalin
Opioid Receptors
Ventricular Fibrillation
Radioisotopes
Ligands
Cardiac Myocytes
Myocardium

Keywords

  • Arrhythmias
  • Cold
  • Ligands of μ- and δ-receptors

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Effect of ligands of opiate receptors on morphofunctional state of the sympathoadrenal system and electrical stability of the heart in acute cold exposure. / Lishmanov, Yu B.; Kondrat'ev, B. Yu; Maslov, L. N.; Naryzhnaya, N. V.

In: Bulletin of Experimental Biology and Medicine, Vol. 123, No. 2, 02.1997, p. 130-132.

Research output: Contribution to journalArticle

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