Effect of combined modality treatment with intraoperative radiation therapy on morphofunctional state of the myocardium in patients with III stage lung cancer

A. Yu Dobrodeev, A. A. Zavyalov, V. I. Chernov, S. A. Tuzikov, L. I. Musabaeva, I. G. Sinilkin

Research output: Contribution to journalArticle

Abstract

Epy influence of combined treatment including neoadjuvant chemotherapy, radical surgery and intraoperative radiotherapy with a single dose of 15 Gr or 10 Gr has been studied in conditions of radiosensibilization on morphological and functional status of myocardium in non-small lung cancer patients at stage III with by means of ECG-synchronized single-photon emission computed tomography of myocardium with 99mTc MIBI. It was shown that this kind of treatment does not worsen functional status of myocardium, besides the perfusion level of myocardium correlated with with initial concomitant cardiovascular pathology and extent of surgical treatment.

Original languageEnglish
Pages (from-to)620-626
Number of pages7
JournalVoprosy Onkologii
Volume58
Issue number5
Publication statusPublished - 2012
Externally publishedYes

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Lung Neoplasms
Myocardium
Radiotherapy
Surgical Pathology
Neoadjuvant Therapy
Therapeutics
Single-Photon Emission-Computed Tomography
Electrocardiography
Perfusion
Drug Therapy

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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Effect of combined modality treatment with intraoperative radiation therapy on morphofunctional state of the myocardium in patients with III stage lung cancer. / Dobrodeev, A. Yu; Zavyalov, A. A.; Chernov, V. I.; Tuzikov, S. A.; Musabaeva, L. I.; Sinilkin, I. G.

In: Voprosy Onkologii, Vol. 58, No. 5, 2012, p. 620-626.

Research output: Contribution to journalArticle

Dobrodeev, A. Yu ; Zavyalov, A. A. ; Chernov, V. I. ; Tuzikov, S. A. ; Musabaeva, L. I. ; Sinilkin, I. G. / Effect of combined modality treatment with intraoperative radiation therapy on morphofunctional state of the myocardium in patients with III stage lung cancer. In: Voprosy Onkologii. 2012 ; Vol. 58, No. 5. pp. 620-626.
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