Early and 3-year follow-up results of coronary by-pass operation in ischemic heart disease patients with moderate dyslipoproteinemia

A. T. Teplyakov, V. D. Aptekar, E. Yu Kolomin, A. A. Garganeeva, A. M. Chernyavsky, I. V. Lusta, V. I. Chernov, R. S. Karpov

Research output: Contribution to journalArticlepeer-review


Aim. The study of efficacy of rehabilitation and clinical-instrumental characteristics of coronary failure in patients with ischemic heart disease (IHD) of high functional classes and moderate dyslipoproteinemia early (1.6 months) and late (1 and 3 years) after coronary by-pass operation. Materials and methods. The examination covered 119 males with IHD (mean age 51.8 ± 6.9 years) 1.6 months and 3 years after coronary by-pass operation. Lipid spectrum of blood plasm, frequency of anginal attacks, 24-h nitroglycerin requirement, results of bicycle exercise and loading myocardial scintigraphy were assessed. The patients were divided into two groups. In 82 patients of group I total cholesterol ranged within 3 years after the surgery from 5.2 to 6.5 mmol/l, 37 patients of group 2 had no lipid disorders. Results, Within 12 months after direct myocardial revascularization, the groups had similar clinical-instrumental characteristics. 3 years after the operation, patients of group 1 exhibited a rise in anginal attacks frequency, nitroglycerin requirement, size of unstable perfusion defects by 84.6, 88.8 and 26.4%, respectively. Exercise tolerance diminished by 18.7%. Conclusion. Moderate defects in lipid metabolism influence progression of coronary failure. This becomes especially pronounced within 3 years after coronary by-pass operation.

Original languageEnglish
Pages (from-to)35-38
Number of pages4
JournalTerapevticheskii Arkhiv
Issue number12
Publication statusPublished - 1998


  • Aortocoronary shunting
  • Hypercholesterolemia
  • Ischemic heart disease
  • Long-term results
  • Normolipidemia

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism

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