Disorders of spatial working memory in affective disorders with mild current depression and their neurophysiological correlates

S. A. Galkin, A. G. Peshkovskaya, G. G. Simutkin, S. N. Vasil’eva, O. V. Roshchina, S. A. Ivanova, N. A. Bokhan

Research output: Contribution to journalArticlepeer-review

Abstract

Objective. To assess spatial working memory disorders in patients with mild depressive disorders and determine their neurophysiological correlates. Material and methods. Thirty patients (right-handed) with ICD-10 diagnosis Mood Disorders (F31.3, F32.0, F33.0, F34.1), aged 37±8 years, were examined before treatment. A control group included 30 mentally and somatically healthy individuals (32±7 years old). The study of spatial working memory was carried out using the Corsi Block-Tapping test. EEG was recorded and the values of the spectral power of theta, alpha and beta rhythms were analyzed. Results and conclusion. A decrease in the level of working memory that was correlated with higher values of theta rhythm power in the frontal and occipital regions and alpha rhythm in the frontal cortex was observed in affective disorders with mild depressive symptoms.

Original languageEnglish
Pages (from-to)56-61
Number of pages6
JournalZhurnal Nevrologii i Psihiatrii imeni S.S. Korsakova
Volume119
Issue number10
DOIs
Publication statusPublished - 2019
Externally publishedYes

Keywords

  • Cognitive functions
  • Depression
  • Electroencephalographic correlates
  • Spatial working memory

ASJC Scopus subject areas

  • Clinical Neurology
  • Psychiatry and Mental health

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