TY - GEN
T1 - Development of radioactive sources on the basis of bioinert ceramic materials for medical applications and their pre-clinical testing
AU - Khabas, Tamara
AU - Kulinich, Ekaterina
AU - Merkulov, Victor
AU - Roesli, Christoph
AU - Martusevich, Mihail
PY - 2014
Y1 - 2014
N2 - In this article, both the composition and composite properties of radioactive sources for medical applications are worked out and studied. The bases of these sources are bioinert ceramic solids and radionuclides. The active source is constituted from dispersed radioactive yttriа oxide or strontium oxide monolithically encapsulated with bioinert glass flux. The thermal expansion properties of the analyzed composites are highly similar to the ones of both titanium metal and titanum alloys. Therefore, the developed radioactive sources can be mounted on titanium holder. Importantly, all utilized elements and alloys are already applied in medicine. In this article we demonstrate the use of a radioactive β-source placed on a titanium holder. The device is finally applied in a oncological model disease treatment.
AB - In this article, both the composition and composite properties of radioactive sources for medical applications are worked out and studied. The bases of these sources are bioinert ceramic solids and radionuclides. The active source is constituted from dispersed radioactive yttriа oxide or strontium oxide monolithically encapsulated with bioinert glass flux. The thermal expansion properties of the analyzed composites are highly similar to the ones of both titanium metal and titanum alloys. Therefore, the developed radioactive sources can be mounted on titanium holder. Importantly, all utilized elements and alloys are already applied in medicine. In this article we demonstrate the use of a radioactive β-source placed on a titanium holder. The device is finally applied in a oncological model disease treatment.
KW - Ceramics
KW - Glass
KW - Live tissue reaction
KW - Ophthalmic applicator
KW - Profilometry
KW - Radiometric measurements
KW - Radionuclides
UR - http://www.scopus.com/inward/record.url?scp=84913582120&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84913582120&partnerID=8YFLogxK
U2 - 10.4028/www.scientific.net/AMR.1040.286
DO - 10.4028/www.scientific.net/AMR.1040.286
M3 - Conference contribution
AN - SCOPUS:84913582120
SN - 9783038352648
VL - 1040
T3 - Advanced Materials Research
SP - 286
EP - 291
BT - Advanced Materials Research
PB - Trans Tech Publications Ltd
T2 - International Conference for Young Scientists “High Technology: Research and Applications 2014”, HTRA 2014
Y2 - 26 March 2014 through 28 March 2014
ER -