Development of radioactive sources on the basis of bioinert ceramic materials for medical applications and their pre-clinical testing

Tamara Khabas, Ekaterina Kulinich, Victor Merkulov, Christoph Roesli, Mihail Martusevich

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

In this article, both the composition and composite properties of radioactive sources for medical applications are worked out and studied. The bases of these sources are bioinert ceramic solids and radionuclides. The active source is constituted from dispersed radioactive yttriа oxide or strontium oxide monolithically encapsulated with bioinert glass flux. The thermal expansion properties of the analyzed composites are highly similar to the ones of both titanium metal and titanum alloys. Therefore, the developed radioactive sources can be mounted on titanium holder. Importantly, all utilized elements and alloys are already applied in medicine. In this article we demonstrate the use of a radioactive β-source placed on a titanium holder. The device is finally applied in a oncological model disease treatment.

Original languageEnglish
Title of host publicationAdvanced Materials Research
PublisherTrans Tech Publications Ltd
Pages286-291
Number of pages6
Volume1040
ISBN (Print)9783038352648
DOIs
Publication statusPublished - 2014
EventInternational Conference for Young Scientists “High Technology: Research and Applications 2014”, HTRA 2014 - Tomsk, Russian Federation
Duration: 26 Mar 201428 Mar 2014

Publication series

NameAdvanced Materials Research
Volume1040
ISSN (Print)10226680
ISSN (Electronic)16628985

Other

OtherInternational Conference for Young Scientists “High Technology: Research and Applications 2014”, HTRA 2014
CountryRussian Federation
CityTomsk
Period26.3.1428.3.14

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Keywords

  • Ceramics
  • Glass
  • Live tissue reaction
  • Ophthalmic applicator
  • Profilometry
  • Radiometric measurements
  • Radionuclides

ASJC Scopus subject areas

  • Engineering(all)

Cite this

Khabas, T., Kulinich, E., Merkulov, V., Roesli, C., & Martusevich, M. (2014). Development of radioactive sources on the basis of bioinert ceramic materials for medical applications and their pre-clinical testing. In Advanced Materials Research (Vol. 1040, pp. 286-291). (Advanced Materials Research; Vol. 1040). Trans Tech Publications Ltd. https://doi.org/10.4028/www.scientific.net/AMR.1040.286